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Effect of Legal Status of Pharmacy Syringe Sales on Syringe Purchases by Persons Who Inject Drugs in San Francisco and San Diego CA

机译:加利福尼亚州圣迭戈和圣地亚哥的药房注射器销售法律地位对注射毒品的人购买注射器的影响

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摘要

Sharing blood-contaminated syringes is the main risk factor for acquiring and transmitting blood-borne infections among persons who inject drugs (PWID). To reduce this risk, in 2005, California enacted legislation allowing local health jurisdictions to legalize non-prescription syringe sales after approving a disease prevention demonstration project (DPDP). With San Francisco approving a DPDP immediately and San Diego never approving one, we compared PWID across cities for their use of pharmacies PWID to obtain syringes. PWID age 18–30 years old were recruited into separate studies in San Francisco (n=243) and San Diego (n=338) between 2008 and 2011. We used multivariable logistic regression to compare the proportions of PWID who obtained syringes from pharmacies by city while controlling for socio-demographics, injection practices and other risk behaviors. Overall, most PWID were white (71%), male (63%), and between the ages of 18–25 years (55%). Compared to San Francisco, a smaller proportion of PWID in San Diego had bought syringes from pharmacies in the prior three months (16.9% vs. 49.8%; p<0.001), which remained statistically significant after adjusting for socio-demographic and behavioral factors (adjusted odds ratio=4.45, 95% confidence interval: 2.98, 6.65). Use of pharmacies to obtain syringes was greater where it was legal to do so. Public health policy can influence HIV and hepatitis C associated risk among PWID; however, implementation of these policies is crucial for the benefits to be realized.
机译:共用被血液污染的注射器是在注射毒品者之间获取和传播血源性感染的主要危险因素。为了降低这种风险,加利福尼亚州于2005年颁布了立法,允许地方卫生管辖区在批准疾病预防示范项目(DPDP)之后使非处方注射器销售合法化。由于旧金山立即批准了DPDP,而圣地亚哥从未批准过DPDP,我们比较了各个城市的PWID,以了解他们使用药房PWID获得注射器的情况。 18至30岁的PWID在2008年至2011年期间分别在旧金山(n = 243)和圣地亚哥(n = 338)进行了独立研究。我们使用多因素logistic回归比较了从药房购买注射器的PWID的比例同时控制社会人口统计资料,注射行为和其他风险行为。总体而言,大多数PWID是白人(71%),男性(63%)以及18-25岁(55%)之间的。与旧金山相比,圣地亚哥的PWID在前三个月内从药房购买了注射器的比例较小(16.9%比49.8%; p <0.001),在调整了社会人口统计学和行为因素后,该数据仍具有统计学意义(调整后的优势比= 4.45,95%置信区间:2.98,6.65)。在合法的情况下,使用药房购买注射器的可能性更大。公共卫生政策可以影响PWID中与HIV和丙型肝炎相关的风险;但是,这些政策的实施对于实现收益至关重要。

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