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Mesenchymal Stem Cells Increase T-Regulatory Cells and Improve Healing Following Trauma and Hemorrhagic Shock (MSCs Increase Tregs and Improve Healing After T/HS)

机译:间质干细胞增加创伤和失血性休克后的T调节细胞并改善愈合(MSCs增加Treg并改善T / HS后的愈合)

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摘要

BackgroundRodent lungs undergo full histologic recovery within one week following unilateral lung contusion (LC). However, when LC is followed by hemorrhagic shock (HS), healing is impaired. We hypothesize that the intravenous administration of mesenchymal stem cells (MSC) to animals undergoing combined LC followed by HS (LCHS) will improve wound healing.
机译:背景啮齿动物的肺在单侧肺挫伤(LC)后的一周内经历了完整的组织学恢复。但是,当LC伴有失血性休克(HS)时,愈合会受到损害。我们假设对先后进行联合LC和HS(LCHS)的动物静脉注射间充质干细胞(MSC)将改善伤口愈合。

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