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Liver Sharing and Organ Procurement Organization Performance under Redistricted Allocation

机译:限制分配下的肝脏共享和器官采购组织绩效

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摘要

Concerns have been raised that optimized redistricting of liver allocation areas might have the unintended result of shifting livers from better-performing to poorer-performing OPOs. We used the Liver Simulated Allocation Model to simulate a 5-year period of liver sharing within either 4 or 8 optimized districts. We investigated whether each OPO’s net liver import under redistricting would be correlated with two OPO performance metrics (observed to expected liver yield and liver donor conversion ratio), along with two other potential correlates (eligible deaths and incident listings above MELD 15). We found no evidence that livers would flow from better-performing OPOs to poorer-performing OPOs in either redistricting scenario. Instead, under these optimized redistricting plans, our simulations suggest that livers would flow from OPOs with more-than-expected eligible deaths toward those with fewer-than-expected eligible deaths, and that livers would flow from OPOs with fewer-than-expected incident listings to those with more-than-expected incident listings, the latter a pattern already established in the current allocation system. Redistricting liver distribution to reduce geographic inequity is expected to align liver allocation across the country with the distribution of supply and demand, rather than transferring livers from better-performing OPOs to poorer-performing OPOs.
机译:有人担心,优化分配肝脏区域的重新分配可能会导致意料不到的结果,即肝脏从性能更好的OPO转变为性能较差的OPO。我们使用肝脏模拟分配模型来模拟在4个或8个优化区域内的5年肝脏共享期。我们调查了重新分配下每个OPO的净肝脏进口量是否与两个OPO绩效指标(观察到的预期肝产量和肝供体转化率)以及其他两个潜在的相关指标(合格死亡和超过MELD 15的事件清单)相关联。我们没有发现证据表明,在两种限制条件下,肝脏都会从性能更好的OPO变为性能较差的OPO。相反,在这些优化的重新分配计划下,我们的模拟表明,肝脏将从合格死亡人数超出预期的OPO向那些合格死亡人数少于预期的OPO流动,肝脏将从事故少于预期的OPO流出对于那些具有超出预期的事件列表的列表,后者是当前分配系统中已经建立的一种模式。重新限制肝脏分布以减少地理不平等现象,有望使全国范围内的肝脏分配与供求的分布保持一致,而不是将肝脏从表现较好的OPO转移到表现较差的OPO。

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