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Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age?

机译：脑膜炎球菌血清群C破伤风类毒素共轭加强疫苗接种后九年的青少年中IgG和IgA记忆B细胞的不同动力学：引发年龄的作用？

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BackgroundAntibody levels wane rapidly after Meningococcal serogroup C conjugate (MenCC) vaccination in young children, rendering the need for an adolescent booster dose. It is not clear whether circulating memory B cells are associated with persistence of MenC-specific antibody levels.

机译：背景脑膜炎球菌血清C结合群（MenCC）疫苗接种后，年幼的儿童抗体水平迅速下降，这需要青少年加强剂量。尚不清楚循环记忆B细胞是否与MenC特异性抗体水平的持续存在有关。

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期刊名称 other
作者
Susanne P. Stoof; Anne-Marie Buisman; Debbie M. van Rooijen; Rianne Boonacker; Fiona R. M. van der Klis; Elisabeth A. M. Sanders; Guy A. M. Berbers;
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年(卷),期 -1(10),10
年度 -1
页码 e0138665
总页数 12
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1. Immunogenicity, Safety and Antibody Persistence of a Booster Dose of Quadrivalent Meningococcal ACWY-tetanus Toxoid Conjugate Vaccine Compared with Monovalent Meningococcal Serogroup C Vaccine Administered Four Years After Primary Vaccination Using the Same Vaccines [J] . Vesikari Timo, Forsten Aino, Bianco Veronique, The Pediatric infectious disease journal . 2015,第12期

机译：初次接种四年后使用相同疫苗接种的四价脑膜炎球菌ACWY-破伤风类毒素共轭疫苗与单价脑膜炎球菌血清C组疫苗加强剂量的免疫原性，安全性和抗体持久性
2. Salivary antibody levels in adolescents in response to a meningococcal serogroup C conjugate booster vaccination nine years after priming: systemically induced local immunity and saliva as potential surveillance tool [J] . Stoof Susanne P., van der Klis Fiona R. M., van Rooijen Debbie M., Vaccine . 2015,第32期

机译：初次接种疫苗后九年，青少年对脑膜炎球菌C群血清白蛋白结合物加强疫苗的唾液抗体水平：全身诱导的局部免疫和唾液可能是监测工具
3. Efficacy and safety of a booster dose of the meningococcal A, C, W, Y-tetanus toxoid conjugate vaccine administered 10 years after primary vaccination and long-term persistence of tetanus toxoid conjugate or polysaccharide vaccine [J] . Human vaccines & immunotherapeutics. . 2020,第6期

机译：脑膜炎球菌A，C，W，Y-Tetanus毒素结合疫苗的疗效和安全性的疗效和安全性10年施用初级疫苗接种和Tetanus毒素缀合物或多糖疫苗的长期持续性
4. Secretory IgA Enhances Gut B Cells Priming and Systemic IgG Responses Towards Commensals [D] . Zhou, You. 2019

机译：分泌IgA增强肠b细胞灌注和全身IgG对共生的反应
5. Efficacy and safety of a booster dose of the meningococcal A C W Y-tetanus toxoid conjugate vaccine administered 10 years after primary vaccination and long-term persistence of tetanus toxoid conjugate or polysaccharide vaccine [O] . Beatriz Quiambao, Paula Peyrani, Ping Li, 2020

机译：脑膜炎球菌ACWY-Tetanus毒素缀合物疫苗在一次疫苗接种后10年施用的疗效和安全性染发剂毒素或多糖疫苗的长期持续存在
6. Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age? [O] . Susanne P Stoof, Anne-Marie Buisman, Debbie M van Rooijen, 2015

机译：脑膜炎球菌血清群C C破伤风类毒素结合物加强免疫接种后9年内青少年IgG和Iga记忆B细胞的不同动态：引发年龄的作用？
7. Immunization of Aged Mice with a Pneumococcal Conjugate Vaccine Combined with an Unmethylated CpG-Containing Oligodeoxynucleotide Restores Defective Immunoglobulin G Antipolysaccharide Responses and Specific CD4+-T- Cell Priming to Young Adult Levels [R] . Sen, G., Chen, Q., Snapper, C. M. 2006

机译：用肺炎球菌结合疫苗与未甲基化的含CpG的寡脱氧核苷酸结合免疫老年小鼠，恢复缺陷免疫球蛋白G抗多糖反应和特异性CD4 + -T-细胞引发青少年成人水平

Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age?

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