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Preliminary Evaluation of a Highly Automated Instrument for the Selection of CD34+ Cells from Mobilized Peripheral Blood Stem Cell Concentrates

机译：从动员的外周血干细胞浓缩物中选择CD34 +细胞的高度自动化仪器的初步评估

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BackgroundCell selection is an important part of manufacturing cellular therapies. A new highly automated instrument, the CliniMACS Prodigy, was evaluated for the selection of CD34+ cells from mobilized peripheral blood stem cell (PBSC) concentrates using monoclonal antibodies conjugated to para-magnetic particles.

机译：背景细胞选择是制造细胞疗法的重要组成部分。评估了一种新的高度自动化的仪器CliniMACS Prodigy，使用与顺磁性颗粒偶联的单克隆抗体从动员的外周血干细胞（PBSC）浓缩物中选择CD34 +细胞。

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期刊名称 other
作者
David F Stroncek; Minh Tran; Sue Ellen Frodigh; Virginia David-Ocampo; Jiaqiang Ren; Andre Larochelle; Virginia Sheikh; Irini Sereti; Jeffery L. Miller; Kevin Longin; Marianna Sabatino;
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年(卷),期 -1(56),2
年度 -1
页码 511–517
总页数 15
原文格式 PDF
正文语种
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关键词
CD34+ cells hematopoietic stem cells cell selection;

机译：CD34 +细胞;造血干细胞;细胞选择;

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专利

1. Preliminary evaluation of a highly automated instrument for the selection of CD34+cells from mobilized peripheral blood stem cell concentrates [J] . Stroncek David F., Minh Tran, Frodigh Sue Ellen, Transfusion: The Journal of the American Association of Blood Banks . 2016,第2期

机译：对从动员的外周血干细胞浓缩物中选择CD34 +细胞的高度自动化仪器的初步评估
2. Highly efficient lentiviral gene transfer in CD34+ and CD34+/38-/lin- cells from mobilized peripheral blood after cytokine prestimulation. [J] . Geronimi F, Richard E, Redonnet Vernhet I, Stem Cells . 2003,第4期

机译：细胞因子预刺激后，从动员的外周血中的CD34 +和CD34 + / 38- / lin-细胞中高效慢病毒基因转移。
3. Comparison of Retroviral Transduction Efficiency in CD34+ Cells Derived from Bone Marrow versus G-CSF-Mobilized or G-CSF Plus Stem Cell Factor-Mobilized Peripheral Blood in Nonhuman Primates. [J] . Hematti P, Tuchman S, Larochelle A, Stem Cells . 2004,第6期

机译：非人灵长类动物的骨髓CD34 +细胞与G-CSF动员或G-CSF加干细胞因子动员的外周血中逆转录病毒转导效率的比较。
4. High-speed flow cytometric analysis of nanoparticle targeting to rare leukemic stem cells in peripheral human blood: preliminary in-vitro studies [C] . Christy L. Cooper, James F. Leary Imaging, manipulation, and analysis of biomolecules, cells, and tissues XII . 2014

机译：靶向人外周血中罕见白血病干细胞的纳米颗粒的高速流式细胞术分析：初步的体外研究
5. Ex vivo expansion of umbilical cord blood CD34+ subset hematopoietic stem cells on the covalently immobilized glycosaminoglycan/chitosan membrane surfaces. [D] . Lee, Jae Sam. 2006

机译：脐带血CD34 +亚型造血干细胞在共价固定的糖胺聚糖/壳聚糖膜表面的离体扩增。
6. Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector [O] . Takashi Okumura, Yumi Horie, Chen-Yi Lai, 2019

机译：使用可自动擦除的仙台病毒载体从患者非动员的外周血来源的CD34 +细胞中产生稳定高效的hiPSC
7. 8. Unrelated single cord blood transplants supported by co-infusion of a low number of mobilized peripheral blood highly purified CD34+ cells from a third party donor after low toxicity myeloablative conditioning [O] . Fernandez M.N. 2005

机译：8.低毒性骨髓清除条件治疗后，通过共注入来自第三方供体的少量动员外周血高纯度CD34 +细胞，支持无关的单脐带血移植

Preliminary Evaluation of a Highly Automated Instrument for the Selection of CD34+ Cells from Mobilized Peripheral Blood Stem Cell Concentrates

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