Distinct modulation of allergic T cell responses by subcutaneous versus sublingual allergen-specific immunotherapy

摘要

BackgroundAllergen-specific immunotherapy is the only curative treatment for type I allergy. It can be administered subcutaneously (SCIT) or sublingually (SLIT). The clinical efficacy of these two treatment modalities appears to be similar, but potential differences in the immunological mechanisms involved have not been fully explored.