Second spatial derivative analysis of cortical surface potentials recorded in cat primary auditory cortex using thin film surface arrays: comparisons with multi-unit data

摘要

BackgroundCurrent source density analysis of recordings from penetrating electrode arrays has traditionally been used to examine the layer-specific cortical activation and plastic changes associated with changed afferent input. We report on a related analysis, the second spatial derivative (SSD) of surface local field potentials (LFPs) recorded using custom designed thin-film polyimide substrate arrays.