Histologic Features Associated with Columnar-Lined Esophagus in Distal Esophageal and Gastroesophageal Junction (GEJ) Biopsies from GERD Patients: A Community-Based Population Study

摘要

BackgroundThere are inherent problems with the endoscopic and pathologic criteria for columnar-lined esophagus (CLE). Furthermore, the clinical and biological significance of an irregular squamocolumnar junction (SCJ) is unclear. The aim of this study was to evaluate the association between histologic features in SCJ biopsies and CLE, and to gain insight into the significance of an irregular SCJ.