Clinically Significant Psychiatric Symptoms among Male Carriers of the Fragile X Premutation with and without FXTAS and the Mediating Influence of Executive Functioning

摘要

ObjectivesTo clarify the neuropsychiatric phenotype of fragile X-associated tremor/ataxia syndrome (FXTAS), and assess the extent to which it is mediated by the dysexecutive syndrome that is a major feature of the disorder.