Relative effect potency estimates of dioxin-like activity fordioxins furans and dioxin-like PCBs in adults based on cytochrome P4501A1 and 1B1 gene expression inblood

摘要

BackgroundIn the risk assessment of PCDDs, PCDFs, and dioxin-like (DL) PCBs, regulatory authorities support the use of the toxic equivalency factor (TEF)-scheme derived from a heterogeneous data set of the relative effect potency (REPs) estimates.