Amygdala-Prefrontal Cortical Functional Connectivity During Implicit Emotion Processing Differentiates Youth with Bipolar Spectrum from Youth with Externalizing Disorders

摘要

ObjectiveBoth bipolar spectrum disorders (BPSD) and attention deficit hyperactivity disorder (ADHD) present with emotion-regulation deficits, but require different clinical management. We examined how the neurobiological underpinnings of emotion regulation might differentiate youth with BPSD versus ADHD (and healthy controls, HCs), specifically assessing functional connectivity (FxC) of amygdala-prefrontal circuitry during an implicit emotion processing task.