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Feasibility Studies of a New Event Selection Method to Improve Spatial Resolution of Compton Imaging for Medical Applications

机译:一种新的事件选择方法的可行性研究以提高医学应用康普顿成像的空间分辨率

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摘要

A Compton imaging method for medical applications that includes new energy determination and data filtering techniques has been tested using several point sources with known emission lines. Using a prototype Compton camera, a distance-of-closest approach technique has been employed to determine the initial energy of the incoming γs and to ensure the reconstructed source position is within an acceptable distance from the known γ source location. Further analysis is done by implementing a Compton line filtering technique, keeping only those interactions whose deposited energy in the first interaction matches the theoretical energy deposition predicted by the Compton equation. Using this new event filtering method, we see improvements in the full width at half maximum in the lateral profiles of γ point sources of up to 70% over standard Compton imaging methods, as well as achievable spatial resolutions in the reconstructed images of better than 2 mm. In addition, this new Compton imaging method was able to reconstruct an extended source of γ rays emitted during irradiation of a water tank with a clinical proton radiotherapy beam.
机译:包括新能量测定和数据过滤技术在内的医疗应用康普顿成像方法已经使用已知发射线的多个点源进行了测试。使用原型康普顿相机,已采用最接近距离方法确定入射γ的初始能量,并确保重建的源位置在距已知γ源位置可接受的距离之内。通过实施康普顿线滤波技术来进行进一步分析,仅保留那些在第一次相互作用中沉积能量与康普顿方程预测的理论能量沉积相匹配的相互作用。使用这种新的事件过滤方法,与标准的康普顿成像方法相比,我们发现γ点源横向轮廓的半高全宽改善了70%,并且在重建图像中可获得的空间分辨率优于2毫米另外,这种新的康普顿成像方法能够重建使用临床质子放射治疗束照射水箱期间发射的γ射线的扩展源。

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