DOES WHOLE-BODY PERIODIC ACCELERATION REDUCE NON-MOTOR SYMPTOMS IN PERSONS WITH PARKINSON’S DISEASE?

摘要

Sleep disturbances, depression, and inactivity are common non-motor problems in Parkinson’s disease (PD). The effects of Whole Body Periodic Acceleration (WBPA) in persons with PD on sleep regulation and activity levels have yet to be evaluated.The objective was to assess whether WBPA improves sleep and activity in persons with PD over 4 weeks compared to gender matched controls.Participants included 5 PD and 5 controls (8 men; 2 women), age 74.10 ± 9.25. Activity trackers monitored sleep, awakenings, and step counts over 24 hours for 6 weeks. Baseline measurements included sleep 30 days prior to study, depression (PHQ-9), and Quality of Life (PDQ-8). WBPA duration was 45 minutes, 3 times per week for 4 weeks. A 2 by 6 repeated measure and paired t tests were used to assess data. A significant decrease was found in BP pre vs. post p .019; PD group had improved depression p .025. Minimally Clinically Significant Differences (MCID) were also found in the PD participants, the PSQI (4.25) points. Self-reports for WBPA displayed improvements in depression and sleep. Decreased physical activity in those with mild to moderate PD was evidenced. WBPA may have a significant role in PD management of non-motor symptoms. Further study with larger groups is warranted using WBPA.