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Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers

机译：与非饮酒者相比异质性药物诱发的肝损伤患者的大量饮酒与不良结果无关

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摘要

Background & AimsThe relationship between alcohol consumption and idiosyncratic drug induced liver injury (DILI) is not well understood. We investigated the relationship between heavy consumption of alcohol and characteristics and outcomes of patients with DILI enrolled in the Drug-induced Liver Injury Network (DILIN) prospective study.

机译：背景与目的饮酒与特发性药物性肝损伤（DILI）之间的关系尚不清楚。我们调查了大量饮酒与参加药物诱发性肝损伤网络（DILIN）前瞻性研究的DILI患者的特征和结局之间的关系。

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期刊名称 other
作者
Lara Dakhoul; Marwan Ghabril; Jiezhun Gu; Victor Navarro; Naga Chalasani; Jose Serrano;
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年(卷),期 -1(16),5
年度 -1
页码 e2
总页数 17
原文格式 PDF
正文语种
中图分类
关键词
Drug Induced Liver Injury Drug Induced Liver Injury Network Significant alcohol consumption RUCAM Chronic DILI ALT;

机译：药物引起的肝损伤;药物引起的肝损伤网络;大量饮酒;RUCAM;慢性DILI;ALT;

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专利

1. Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers [J] . Dakhoul Lara, Ghabril Marwan, Gu Jiezhun, Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association . 2018,第5期

机译：与非饮酒者相比，患有特质药物诱导的肝损伤的患者的患者的严重消费与较差的蛋白质无关
2. Letter to the Editor Regarding the Article Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury by Cho and Co-Workers, 2019 [J] . Fromenty Bernard Chemical research in toxicology . 2020,第1期

机译：关于编辑的信中关于旋转酮的致态毒性毒性，但不会引起显着的肝损伤：对线粒体电子传输链抑制的假设的影响是由Cho和同事的特质药物诱导的肝损伤的常见机制，2019年
3. Response to the Letter to the Editor Concerning the Article "Rotenone Increases Isoniazid Toxicity but Does Not Cause Liver Injury: Implications for the Hypothesis That Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury" by Bernard Fromenty [J] . Cho Tiffany, Uetrecht Jack Chemical research in toxicology . 2020,第1期

机译：对关于文章的信函的回应“RotenOne增加了异维毒性，但不会引起肝损伤：对假设的影响，抑制线粒体电子传输链是一种常见的特质药物诱导肝损伤的机制”Bernard从大伯纳德开始
4. A Drug-Induced Liver Injury Prediction Model using Transcriptional Response Data with Graph Neural Network [C] . Doyeong Hwang, Minji Jeon, Jaewoo Kang IEEE International Conference on Big Data and Smart Computing . 2020

机译：基于图谱神经网络的转录反应数据的药物诱导的肝损伤预测模型
5. Drug-cytokine cytotoxic interaction: Relationship to idiosyncratic, drug-induced liver injury [D] . Maiuri, Ashley 2015

机译：药物-细胞因子的细胞毒性相互作用：与特异的，药物诱导的肝损伤的关系
6. Idiosyncratic Drug-Induced Liver Injury (DILI) and Herb-Induced Liver Injury (HILI): Diagnostic Algorithm Based on the Quantitative Roussel Uclaf Causality Assessment Method (RUCAM) [O] . Rolf Teschke, Gaby Danan 2021

机译：特质药物诱导的肝损伤（DiRI）和草药诱导的肝损伤（HILI）：基于定量ROOSSEL UCLAF因果关系评估方法的诊断算法（RUCAM）
7. Idiosyncratic Drug-Induced Liver Injury (DILI) and Herb-Induced Liver Injury (HILI): Diagnostic Algorithm Based on the Quantitative Roussel Uclaf Causality Assessment Method (RUCAM) [O] . Rolf Teschke, Gaby Danan 2021

机译：特质药物诱导的肝损伤（DiRI）和草药诱导的肝损伤（HILI）：基于定量ROOSSEL UCLAF因果关系评估方法的诊断算法（RUCAM）

Heavy Consumption of Alcohol is Not Associated With Worse Outcomes in Patients With Idiosyncratic Drug-induced Liver Injury Compared to Non-Drinkers

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