Comparison of BOLD fMRI and Provocative DSC Perfusion MR Imaging for Monitoring Cerebrovascular Reserve in Intracranial Chronic Cerebrovascular Disease

摘要

Background and Purpose.Loss of hemodynamic reserve (HR) in intracranial cerebrovascular disease (CVD) reduces blood oxygenation level dependent (BOLD) activation by fMRI and increases asymmetry in MTT measured by provocative DSC perfusion MRI before and after vasodilatation with intravenous acetazolamide. The concordance for detecting HR integrity has been compared.