Phase II trial of capecitabine plus nab-paclitaxel in patients with metastatic pancreatic adenocarcinoma

机译：卡培他滨联合纳布-紫杉醇治疗转移性胰腺癌的II期临床研究

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BackgroundCombination chemotherapy regimens including fluoropyrimidines as well as albumin-bound paclitaxel have shown promising results in patients with metastatic pancreatic adenocarcinoma (mPC). Based on the recently described excellent therapeutic index of capecitabine plus nab-paclitaxel in metastatic breast cancer, the present phase II trial was initiated.

机译：背景包括氟嘧啶和白蛋白结合的紫杉醇在内的联合化疗方案已在转移性胰腺腺癌（mPC）患者中显示出令人鼓舞的结果。基于最近描述的卡培他滨加纳布-紫杉醇在转移性乳腺癌中的优异治疗指数，启动了目前的II期试验。

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期刊名称 Journal of Gastrointestinal Oncology
作者
Werner Scheithauer; Gabriela Kornek; Gerald Prager; Nadja Stranzl; Friedrich Laengle; Martin Schindl; Josef Friedl; Julia Klech; Sabine Roethlin; Christoph Zielinski;
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作者单位

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年(卷),期 2016(7),2
年度 2016
页码 234–238
总页数 5
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Phase II trial of capecitabine plus nab-paclitaxel in patients with metastatic pancreatic adenocarcinoma [J] . Werner Scheithauer, Gabriela Kornek, Gerald Prager, Journal of Gastrointestinal Oncology . 2015,第2期

机译：卡培他滨联合纳布-紫杉醇治疗转移性胰腺癌的II期临床研究
2. Biweekly high-dose gemcitabine alone or in combination with capecitabine in patients with metastatic pancreatic adenocarcinoma: a randomized phase II trial. [J] . Scheithauer W, Schull B, Ulrich Pur H, Annals of oncology: official journal of the European Society for Medical Oncology . 2003,第1期

机译：转移性胰腺腺癌患者每两周一次大剂量吉西他滨或联合卡培他滨治疗：一项II期随机试验。
3. nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma: Canadian Subgroup Analysis of the Phase 3 MPACT Trial (vol 33, pg 747, 2016) [J] . Tehfe Mustapha, Dowden Scot, Kennecke Hagen, Advances in therapy. . 2017,第1期

机译：Nab-Paclitaxel加吉西他滨与吉西他滨，转移胰腺炎患者：加拿大亚群分析阶段3 MPACT试验（第33 Vol 33，PG 747,2016）
4. Preliminary results of a phase I/II clinical trial using in situ photoimmunotherapy combined with imiquimod for metastatic melanoma patients [C] . Xiaosong Li, Mark F. Naylor, Robert E. Nordquist, . 2010

机译：使用原位光免疫疗法联合咪喹莫特治疗转移性黑色素瘤患者的I / II期临床试验的初步结果
5. Recruitment, retention and compliance in randomized, phase III clinical trials involving obese patients diagnosed with type 2 Diabetes Mellitus with respect to weight loss practicum report. [D] . Mithani, Moez S. 2012

机译：涉及诊断为2型糖尿病的肥胖患者的有关减肥实践的随机III期临床试验中的招募，保留和依从性报告。
6. Phase 1B trial of Nab-paclitaxel plus gemcitabine capecitabine and cisplatin (PAXG regimen) in patients with unresectable or borderline resectable pancreatic adenocarcinoma [O] . Michele Reni, Gianpaolo Balzano, Silvia Zanon, 2016

机译：Nab-紫杉醇联合吉西他滨卡培他滨和顺铂（PAXG方案）在无法切除或边缘切除的胰腺腺癌患者的1B期临床试验
7. Ibrutinib in combination with nab-paclitaxel and gemcitabine for first-line treatment of patients with metastatic pancreatic adenocarcinoma: phase III RESOLVE study [O] . M. Tempero, D.-Y. Oh, J. Tabernero, 2021

机译：Ibrutinib与Nab-Paclitaxel和吉西他滨组合用于转移性胰腺腺癌患者的一线治疗：III期决议研究

Phase II trial of capecitabine plus nab-paclitaxel in patients with metastatic pancreatic adenocarcinoma

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