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Evidence Supporting Selective Dorsal Rhizotomy for Treatment of Spastic Cerebral Palsy

机译:证据支持选择性背根神经切断术治疗痉挛性脑瘫

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摘要

The objective of this review is to analyze the evidence supporting selective dorsal rhizotomy (SDR) for the treatment of spastic cerebral palsy (CP). We reviewed 85 outcome studies from 12 countries between 1990 and 2017. The published results are overwhelmingly supportive of SDR, and 39 studies form a basis for this review. Also included is some of the clinical experience of the senior author.The results show that SDR plus postoperative physiotherapy (PT) improved gait, functional independence, and self-care in children with spastic diplegia. In adults with a follow-up of 20 to 28 years, the early improvements after childhood SDR were sustained and improved quality of life. Furthermore, majority of the adults who underwent SDR as children would recommend SDR to others. On the clinical side, while SDRs through multilevel laminectomies or laminoplasty were associated with spinal deformities (i.e., scoliosis, hyperlordosis, kyphosis, spondylolisthesis, spondylolysis, and nonhealing of laminoplasty), SDRs through a single level laminectomy prevented SDR-related spinal problems. The outcomes of SDR specific to spastic quadriplegia require further investigation because of the relatively small patient population with quadriplegia. Lastly, we found that SDR can prevent or reverse premature aging in adolescents and adults with spastic diplegia. In conclusion, the evidence supporting the efficacy of SDR is strong, and SDR is a well-established option for spasticity management in spastic CP.
机译:这篇综述的目的是分析支持选择性背脊神经切开术(SDR)治疗痉挛性脑瘫(CP)的证据。我们审查了1990年至2017年间来自12个国家/地区的85项结局研究。已发表的结果绝大多数支持SDR,其中39项研究构成了此次审查的基础。还包括该高级作者的一些临床经验。结果表明,SDR加术后物理治疗(PT)可改善痉挛性截瘫患儿的步态,功能独立性和自我保健。在随访期为20至28年的成人中,儿童SDR后的早期改善得以持续并改善了生活质量。此外,大多数在儿童时期经历过特别提款权的成年人会向其他人推荐特别提款权。在临床方面,尽管通过多级椎板切开术或椎板成形术进行的SDR与脊柱畸形(即脊柱侧弯,肥大,脊柱后凸,脊柱滑脱,脊椎软化和椎板成形术不愈合)相关,但通过单层椎板切除术进行的SDR可以预防与SDR相关的脊柱问题。由于痉挛性四肢瘫痪的患者特别少,因此SDR的结局需要进一步研究。最后,我们发现SDR可以预防或逆转患有痉挛性截瘫的青少年和成年人。总之,支持SDR疗效的证据很充分,SDR是痉挛性CP痉挛管理的行之有效的选择。

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