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Treatment of diaphyseal pathological fractures in children with monostotic fibrous dysplasia using cortical strut allografts and internal plating

机译:皮层支撑同种异体骨内固定治疗单核纤维异型增生患儿骨干病理骨折。

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摘要

Children with fibrous dysplasia (FD) chronically suffer from pain, pathological fractures, and limb deformities. The most effective methods for managing the associated pathological fractures remain controversial. The purpose of this study was to evaluate the clinical results of the treatment of diaphyseal pathological fractures in children with monostotic fibrous dysplasia (MFD) using cortical strut allografts and internal plating.We retrospectively analyzed outcomes in nine children (5 boys, 4 girls) with diaphyseal pathological fractures due to MFD, who were treated with cortical strut allografts and internal plating (6 femoral fractures and 3 humeral fractures) between July 2007 and November 2012. The median age of patients in our study was 10 years (range 6–14 years). The fracture healing time, pain, extremity function, refracture, graft resorption, and complications were recorded to evaluate treatment effects.The median time of follow-up was 69 months (range 60–75 months). All patients had good postoperative fracture healing with a median healing time of 14 weeks (range 12–16 weeks). None experienced refracture, graft resorption, nerve injury, or limitation of extremity function or other complications. The fixation remained stable in all patients, with no evidence of loosening screws after surgery.In pediatric patients, the described surgical approach is an effective and reliable treatment method for diaphyseal pathological fractures caused by MFD. Cortical strut allografts, which act as biological bone plates, can provide good mechanical support while increasing the rate of fracture union.
机译:患有纤维异常增生(FD)的儿童长期患有疼痛,病理性骨折和肢体畸形。处理相关病理性骨折的最有效方法仍存在争议。这项研究的目的是评估同种异体皮质支柱同种异体移植和内钢板治疗儿童单发性纤维状异型增生(MFD)的骨干病理性骨折的临床结果。我们回顾性分析了9例儿童(5例男孩,4例女孩)在2007年7月至2012年11月之间,因MFD引起的干phy端病理性骨折接受了皮质支撑杆同种异体移植和内部钢板治疗(6例股骨骨折和3例肱骨骨折)。我们研究的患者中位年龄为10岁(范围为6-14岁) )。记录骨折愈合时间,疼痛,四肢功能,骨折,移植物再吸收和并发症,以评估治疗效果。中位随访时间为69个月(范围60-75个月)。所有患者术后骨折愈合良好,中位愈合时间为14周(范围12–16周)。没有人发生骨折,移植物吸收,神经损伤,肢体功能受限或其他并发症。所有患者的固定均保持稳定,没有手术后螺钉松动的迹象。在儿科患者中,所描述的手术方法是一种有效而可靠的治疗方法,可用于治疗由MFD引起的骨干病理性骨折。充当生物骨板的皮质支撑同种异体移植物可以提供良好的机械支撑,同时增加骨折愈合的速度。

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