Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro

机译：胞质IVa磷脂酶A2介导IL-8 / CXCL8诱导的人多形核白细胞体外迁移

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BackgroundCytosolic gIVaPLA2 is a critical enzyme in the generation of arachidonate metabolites and in induction of β2-integrin adhesion in granulocytes. We hypothesized that gIVaPLA2 activation also is an essential downstream step for post adhesive migration of PMN in vitro.

机译：背景胞质gIVaPLA2是花生四烯酸代谢产物的产生和粒细胞中β2-整合素粘附诱导的关键酶。我们假设gIVaPLA2激活也是PMN在体外粘附后迁移的重要下游步骤。

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期刊名称 Journal of Inflammation (London England)
作者
Angelo Y Meliton; Nilda M Muñoz; Lucille N Meliton; David C Binder; Christopher M Osan; Xiangdong Zhu; Steven M Dudek; Alan R Leff;
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年(卷),期 2010(7),-1
年度 2010
页码 14
总页数 8
原文格式 PDF
正文语种
中图分类免疫学;
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专利

1. Cytosolic group IVa phospholipase A₂mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro [J] . Angelo Y Meliton, Nilda M Mu?oz, Lucille N Meliton, Journal of inflammation. . 2010,第4期

机译：胞质IVa磷脂酶A _{2 介导IL-8 / CXCL8诱导的人多形核白细胞体外迁移}
2. Inhibition of Group IVA Cytosolic Phospholipase A2 by Thiazolyl Ketones in Vitro, ex Vivo, and in Vivo [J] . George Kokotos, Astrid J. Feuerherm, Efrosini Barbayianni, Journal of Medicinal Chemistry . 2014,第18期

机译：噻唑基酮在体外，离体和体内抑制IVA族胞质磷脂酶A2
3. Cytosolic phospholipase A2 group IVA influence on GM-CSF expression in human lung cells: A pilot study [J] . Milena Sokolowska, Joanna Stefanska, Karolina Wodz-Naskiewicz, Medical science monitor : . 2010,第1期

机译：胞质磷脂酶A2组IVA对人肺细胞GM-CSF表达的影响：一项初步研究
4. LYSOPHOSPHATIDYLCHOLINE AND PHOSPHOLIPASE A_2 AFFECT THE OXIDATIVE ACTIVITY OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES [C] . M PETKOVIC, J MUELLER, J SCHILLER, 12th Symposium on Bioluminescence and Chemiluminescence, Apr 5-9, 2002, Robinson College, University of Cambridge, UK . 2002

机译：脂磷脂酰胆碱和磷脂酶A_2影响人多核白细胞的氧化活性。
5. Mass Spectrometric Analysis of Specificity and Inhibition of Group IVA Cytosolic Phospholipase A2 on Natural Membrane Phospholipids. [D] . Chen, Yuan. 2015

机译：质谱分析IVA胞质磷脂酶A2对天然膜磷脂的特异性和抑制作用。
6. Intracellular Actions of Group IIA Secreted Phospholipase A2 and Group IVA Cytosolic Phospholipase A2 Contribute to Arachidonic Acid Release and Prostaglandin Production in Rat Gastric Mucosal Cells and Transfected Human Embryonic Kidney Cells [O] . Zhanglin Ni, Nicole M. Okeley, Brian P. Smart, -1

机译：IIA组分泌的磷脂酶A2和IVA组胞质磷脂酶A2的细胞内作用有助于大鼠胃粘膜细胞和转染的人胚肾细胞中花生四烯酸的释放和前列腺素的产生
7. Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro [O] . Angelo Y Meliton, Nilda M Muñoz, Lucille N Meliton, 2010

机译：胞质IVa磷脂酶A2介导IL-8 / CXCL8诱导的人多形核白细胞体外迁移

Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro

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