Three new lycopodine-type alkaloids, 4α-hydroxyanhydrolycodoline (>1), 4α,6α-dihydroxyanhydrolycodoline (>2), and 6-epi-8β-acetoxylycoclavine (>3), and an artifact, lycoposerramine G nitrate (>4), along with seventeen related known compounds, were isolated from the club moss Lycopodiumjaponicum Thunb. ex Murray (Lycopodiaceae). Their structures were elucidated by extensive spectroscopic methods as well as X-ray analysis. Compounds >1–>4 were evaluated for their acetylcholine esterase inhibitory activity.Electronic supplementary materialThe online version of this article (doi:10.1007/s13659-014-0027-1) contains supplementary material, which is available to authorized users.
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