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Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease

机译：高效雾化器雾化溴比邻吡咯酸盐治疗慢性阻塞性肺疾病的疗效和安全性

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AimsTo establish the dose−response for pharmacodynamics (bronchodilatation), safety and pharmacokinetics for a nebulized formulation of the long acting muscarinic antagonist glycopyrrolate (EP-101) with a high efficiency nebulizer in patients with chronic obstructive pulmonary disease (COPD).

机译：目的为慢性阻塞性肺疾病（COPD）患者建立长效毒蕈碱拮抗剂格隆溴铵（EP-101）与高效雾化器雾化制剂的药效学（支气管扩张），安全性和药代动力学剂量反应。

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期刊名称 British Journal of Clinical Pharmacology
作者
Brian R Leaker; Peter J Barnes; C Richard Jones; Ahmet Tutuncu; Dave Singh;
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作者单位

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年(卷),期 2015(79),3
年度 2015
页码 492–500
总页数 9
原文格式 PDF
正文语种
中图分类药学;
关键词
COPD EP-101 glycopyrrolate LAMA muscarinic antagonist nebulizer;

机译：COPD;EP-101;格隆溴铵;LAMA;毒蕈碱拮抗剂;雾化器;

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专利

1. Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease [J] . Leaker Brian R., Barnes Peter J., Jones C. Richard, British Journal of Clinical Pharmacology . 2015,第3期

机译：高效雾化剂雾化的吡咯烷酸盐雾化剂在慢性阻塞性肺疾病患者中的疗效和安全性
2. Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease [J] . Leaker Brian R., Barnes Peter J., Jones C. Richard, British journal of clinical pharmacology . 2015,第3期

机译：高效雾化剂雾化的吡咯烷酸盐雾化剂在慢性阻塞性肺疾病患者中的疗效和安全性
3. Efficacy and safety of revefenacin for nebulization in patients with chronic obstructive pulmonary disease taking concomitant ICS/LABA or LABA: subgroup analysis from phase III trials [J] . Sanjay Sethi, James F. Donohue, Gary T. Ferguson, Therapeutic advances in respiratory disease. . 2020,第12期

机译：慢性阻塞性肺疾病患者伴患者伴有ICS / Laba或Laba的乳腺化术治疗中的疗效和安全性：III期试验的亚组分析
4. Telemedicine Follow Up of Chronic Obstructive Pulmonary Disease Integrated into a Patient-Centered Health Care Team-Setting Impacts on Patient Empowerment and Safety [C] . Berglind Fjola Smaradottir, Rune Fensli, Inger-Alice Naley Aas, International Conference on Computational Science and Computational Intelligence . 2017

机译：慢性阻塞性肺疾病的远程医疗随访已整合到以患者为中心的医疗团队中-对患者赋权和安全的影响
5. Efficacy of DVD technology in chronic obstructive pulmonary disease self-management education of rural patients [D] . Stellefson, Michael Leland 2008

机译：DVD技术在农村地区慢性阻塞性肺疾病自我管理教育中的作用
6. Efficacy and Safety of Nebulized Glycopyrrolate/eFlow® Closed System in Patients with Moderate-to-Very-Severe Chronic Obstructive Pulmonary Disease with Pre-Existing Cardiovascular Risk Factors [O] . Gary T. Ferguson, Robert Tosiello, Shahin Sanjar, 2019

机译：格隆溴铵/eFlow®雾化雾化封闭系统对中度至重度慢性阻塞性肺疾病患者已有心血管危险因素的疗效和安全性
7. Efficacy and Safety of Nebulized Glycopyrrolate/eFlow® Closed System in Patients with Moderate-to-Very-Severe Chronic Obstructive Pulmonary Disease with Pre-Existing Cardiovascular Risk Factors [O] . Gary T. Ferguson, Robert Tosiello, Shahin Sanjar, 2019

机译：具有预先存在的心血管危险因素的中度至非常严重的慢性阻塞性肺疾病患者雾化甘氨酸/EFFLOW®闭合系统的疗效和安全性

Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease

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