首页> 美国卫生研究院文献>Journal of Applied Clinical Medical Physics >Is 5 mm MMLC suitable for VMAT‐based lung SBRT? A dosimetric comparison with 2.5 mm HDMLC using RTOG‐0813 treatment planning criteria for both conventional and high‐dose flattening filter‐free photon beams
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Is 5 mm MMLC suitable for VMAT‐based lung SBRT? A dosimetric comparison with 2.5 mm HDMLC using RTOG‐0813 treatment planning criteria for both conventional and high‐dose flattening filter‐free photon beams

机译:5 mm MMLC是否适合基于VMAT的肺SBRT?使用RTOG-0813治疗计划标准对2.5 mm HDMLC进行剂量学比较用于常规和大剂量平坦化无滤光子光束

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摘要

The aim of this study is to assess the suitability of 5 mm millennium multileaf collimator (MMLC) for volumetric‐modulated arc therapy (VMAT)‐based lung stereotactic body radiotherapy (SBRT). Thirty lung SBRT patient treatment plans along with their planning target volumes (ranging from 2.01 cc to 150.11 cc) were transferred to an inhomogeneous lung phantom and retrospectively planned using VMAT technique, along with the high definition multileaf collimator (HDMLC) and MMLC systems. The plans were evaluated using Radiation Therapy Oncology Group (RTOG‐0813) treatment planning criteria for target coverage, normal tissue sparing, and treatment efficiency for both the MMLC and HDMLC systems using flat and flattening filter‐free (FFF) photon beams. Irrespective of the target volumes, both the MLC systems were able to satisfy the RTOG‐0813 treatment planning criteria without having any major deviation. Dose conformity was marginally better with HDMLC. The average conformity index (CI) value was found to be 1.069 ± 0.034 and 1.075 ± 0.0380 for HDMLC and MMLC plans, respectively. For the 6 MV FFF beams, the plan was slightly more conformal, with the average CI values of 1.063 ± 0.029 and 1.073 ± 0.033 for the HDMLC and MMLC plans, respectively. The high dose spillage was the maximum for 2 cc volume set (3% for HDMLC and 3.1% for MMLC). In the case of low dose spillage, both the MLCs were within the protocol of no deviation, except for the 2 cc volume set. The results from this study revealed that VMAT‐based lung SBRT using 5 mm MMLC satisfies the RTOG‐0813 treatment planning criteria for the studied target size and shapes.PACS numbers: 87.53.Ly, 87.53D, 87.56.jk
机译:这项研究的目的是评估5毫米千年多叶准直仪(MMLC)对基于容积调制弧光疗法(VMAT)的肺立体定向身体放射疗法(SBRT)的适用性。将三十项SBRT肺部患者治疗计划及其计划目标量(范围从2.01 cc到150.11 cc)转移到不均匀的肺部幻影中,并使用VMAT技术以及高清多叶准直仪(HDMLC)和MMLC系统进行回顾性计划。使用放疗和无滤光(FFF)光子束的MMLC和HDMLC系统,使用放射治疗肿瘤学小组(RTOG-0813)治疗计划标准对目标覆盖率,正常组织保留和治疗效率进行评估,评估计划。无论目标量如何,两个MLC系统都能够满足RTOG-0813处理计划标准,而没有任何重大偏差。 HDMLC的剂量一致性略好。 HDMLC和MMLC计划的平均合格指数(CI)值分别为1.069±0.034和1.075±0.0380。对于6 MV FFF光束,该计划更加适形,HDMLC和MMLC计划的平均CI值分别为1.063±0.029和1.073±0.033。高剂量泄漏量是2 cc体积设置的最大值(HDMLC为3%,MMLC为3.1%)。在低剂量泄漏的情况下,除了设定为2 cc的体积外,两个MLC均在操作规程之内。这项研究的结果表明,使用5毫米MMLC的基于VMAT的肺SBRT可以满足RTOG-0813治疗计划的研究目标尺寸和形状的治疗标准.PACS编号:87.53.Ly,87.53D,87.56.jk

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