Dividing without centrioles: innovative plant microtubule organizing centres organize mitotic spindles in bryophytes the earliest extant lineages of land plants

摘要

Background and aimsAs remnants of the earliest land plants, the bryophytes (liverworts, mosses and hornworts) are important in understanding microtubule organization in plant cells. Land plants have an anastral mitotic spindle that forms in the absence of centrosomes, and a cytokinetic apparatus comprised of a predictive preprophase band (PPB) before mitosis and a phragmoplast after mitosis. These microtubule arrays have no counterpart in animal cells and the nature of the plant microtubule organizing centre (MTOC) remained an enigma for many years until antibodies to γ-tubulin, an essential component of the MTOC in all eukaryotes, became available for tracing the origin of microtubule arrays.