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Electromagnetic tracking (EMT) technology for improved treatment quality assurance in interstitial brachytherapy

机译:电磁跟踪(EMT)技术可改善间质近距离放射治疗的治疗质量保证

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摘要

Electromagnetic Tracking (EMT) is a novel technique for error detection and quality assurance (QA) in interstitial high dose rate brachytherapy (HDR‐iBT). The purpose of this study is to provide a concept for data acquisition developed as part of a clinical evaluation study on the use of EMT during interstitial treatment of breast cancer patients. The stability, accuracy, and precision of EMT‐determined dwell positions were quantified. Dwell position reconstruction based on EMT was investigated on CT table, HDR table and PDR bed to examine the influence on precision and accuracy in a typical clinical workflow. All investigations were performed using a precise PMMA phantom. The track of catheters inserted in that phantom was measured by manually inserting a 5 degree of freedom (DoF) sensor while recording the position of three 6DoF fiducial sensors on the phantom surface to correct motion influences. From the corrected data, dwell positions were reconstructed along the catheter's track. The accuracy of the EMT‐determined dwell positions was quantified by the residual distances to reference dwell positions after using a rigid registration. Precision and accuracy were investigated for different phantom‐table and sensor‐field generator (FG) distances. The measured precision of the EMT‐determined dwell positions was ≤ 0.28 mm (95th percentile). Stability tests showed a drift of 0.03 mm in the first 20 min of use. Sudden shaking of the FG or (large) metallic objects close to the FG degrade the precision. The accuracy with respect to the reference dwell positions was on all clinical tables < 1 mm at 200 mm style="fixed-case">FG distance and 120 mm phantom‐table distance. Phantom measurements showed that style="fixed-case">EMT‐determined localization of dwell positions in style="fixed-case">HDR‐ style="fixed-case">iBT is stable, precise, and sufficiently accurate for clinical assessment. The presented method may be viable for clinical applications in style="fixed-case">HDR‐ style="fixed-case">iBT, like implant definition, error detection or quantification of uncertainties. Further clinical investigations are needed.
机译:电磁跟踪(EMT)是一种用于间隙高剂量率近距离放射治疗(HDR-iBT)中的错误检测和质量保证(QA)的新颖技术。这项研究的目的是为乳腺癌患者间质治疗期间使用EMT的临床评估研究提供一部分数据采集概念。对由EMT确定的驻留位置的稳定性,准确性和精确度进行了量化。在CT工作台,HDR工作台和PDR床上研究了基于EMT的驻留位置重构,以研究其对典型临床工作流程中精度和准确性的影响。所有检查均使用精确的PMMA体模进行。通过手动插入5个自由度(DoF)传感器,同时在幻像表面上记录三个6DoF基准传感器的位置以校正运动影响,来测量插入该幻象中的导管的轨迹。根据校正后的数据,沿导管的轨迹重建驻留位置。使用刚性对位后,EMT确定的驻留位置的精度通过到参考驻留位置的剩余距离来量化。研究了不同幻影台和传感器场发生器(FG)距离的精度和准确性。 EMT确定的驻留位置的测量精度为≤0.28 mm(95%)。稳定性测试显示,在使用的前20分钟内漂移为0.03毫米。 FG或靠近FG的(大型)金属物体的突然震动会降低精度。在200 mm style =“ fixed-case”> FG 距离和120 mm幻影台距离上,所有临床工作台上相对参考驻留位置的精度均<1 mm。幻像测量表明, style =“ fixed-case”> EMT -确定了 style =“ fixed-case”> HDR - style =“ fixed-case “> iBT 稳定,精确且足够准确,可用于临床评估。所提出的方法对于 style =“ fixed-case”> HDR - style =“ fixed-case”> iBT 的临床应用可能是可行的,例如植入物定义,错误检测或定量不确定性。需要进一步的临床研究。

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