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Use of a radial projection to reduce the statistical uncertainty of spot lateral profiles generated by Monte Carlo simulation

机译:使用径向投影来减少由蒙特卡洛模拟生成的点横向轮廓的统计不确定性

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摘要

Monte Carlo (MC) simulation has been used to generate commissioning data for the beam modeling of treatment planning system (TPS). We have developed a method called radial projection (RP) for postprocessing of MC‐simulation‐generated data. We used the RP method to reduce the statistical uncertainty of the lateral profile of proton pencil beams with axial symmetry. The RP method takes advantage of the axial symmetry of dose distribution to use the mean value of multiple independent scores as the representative score. Using the mean as the representative value rather than any individual score results in substantial reduction in statistical uncertainty. Herein, we present the concept and step‐by‐step implementation of the RP method, as well as show the advantage of the RP method over conventional measurement methods for generating lateral profile. Lateral profiles generated by both methods were compared to demonstrate the uncertainty reduction qualitatively, and standard error comparison was performed to demonstrate the reduction quantitatively. The comparisons showed that statistical uncertainty was reduced substantially by the RP method. Using the RP method to postprocess MC data, the corresponding MC simulation time was reduced by a factor of 10 without quality reduction in the generated result from the MC data. We concluded that the RP method is an effective technique to increase MC simulation efficiency for generating lateral profiles for axially symmetric pencil beams.
机译:蒙特卡洛(MC)仿真已用于生成调试数据,用于治疗计划系统(TPS)的射线建模。我们开发了一种称为径向投影(RP)的方法,用于对MC模拟生成的数据进行后处理。我们使用RP方法来减少具有轴向对称性的质子笔形束横向轮廓的统计不确定性。 RP方法利用剂量分布的轴向对称性,将多个独立评分的平均值用作代表评分。使用平均值作为代表值而不是任何单个分数会导致统计不确定性大大降低。在此,我们介绍了RP方法的概念和分步实施,并展示了RP方法相对于传统测量方法生成侧向轮廓的优势。比较两种方法生成的横向轮廓,以定性地证明不确定性降低,并进行标准误差比较以定量地表明降低。比较表明,通过RP方法可以显着降低统计不确定性。使用RP方法对MC数据进行后处理,可以将相应的MC仿真时间减少10倍,而不会降低MC数据生成结果的质量。我们得出结论,RP方法是一种有效的技术,可以提高MC模拟效率,以生成轴向对称笔形光束的横向轮廓。

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