Gamma‐aminobutyric acidA receptor agonist muscimol increases KiSS‐1 gene expression in hypothalamic cell models

摘要

PurposeAccumulating evidence indicates that hypothalamic kisspeptin plays a pivotal role in the regulation of the hypothalamic–pituitary–gonadal (HPG) axis. In this study, the direct action of the gamma‐aminobutyric acid (GABA)A receptor agonist on kisspeptin‐expressing neuronal cells was examined.