Beneficial effects of Heqi san on rat model of polycystic ovary syndrome through the PI3K/AKT pathway

机译：和气散通过PI3K / AKT途径对多囊卵巢综合征大鼠模型的有益作用

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摘要

BackgroundHeqi San, a traditional Chinese medicine (TCM) has been reported to regulate hormone levels in patients with metabolic disease, suggesting a potential clinical application. In the current study, we aimed to elucidate the effect of Heqi San on rat model of polycystic ovary syndrome (PCOS).

机译：背景技术据报道，中药合芪散可调节代谢性疾病患者的激素水平，表明其潜在的临床应用前景。在本研究中，我们旨在阐明合芪散对多囊卵巢综合征（PCOS）大鼠模型的影响。

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期刊名称 DARU Journal of Pharmaceutical Sciences
作者
Hengxia Zhao; Daocheng Zhou; Ye Chen; Deliang Liu; Shufang Chu; Shimao Zhang;
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作者单位

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年(卷),期 2017(25),-1
年度 2017
页码 21
总页数 12
原文格式 PDF
正文语种
中图分类药学;
关键词
Polycystic ovary syndrome Heqi san PI3K/AKT pathway miRNA PTEN;

机译：多囊卵巢综合征;和奇散;PI3K / AKT途径;miRNA PTEN;

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专利

1. Guizhi Fuling Wan reduces autophagy of granulosa cell in rats with polycystic ovary syndrome via restoring the PI3K/AKT/mTOR signaling pathway [J] . Liu Min, Zhu Hongqiu, Zhu Ying, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2021,第1期

机译：桂花茯苓通过恢复PI3K / AKT / MTOR信号通路，减少了多囊卵巢综合征的大鼠颗粒细胞的自噬
2. Plumbagin inhibits proliferation and promotes apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inactivating PI3K/Akt/mTOR pathway [J] . Zhaowei Cai, Shaojuan He, Tao Li, Animal Cells and Systems . 2020,第4期

机译：通过灭活PI3K / AKT / MTOR途径抑制肠果抑制多囊卵巢综合征中卵巢粒细胞的增殖和促进卵巢颗粒细胞凋亡
3. Liuwei Dihuang Pills alleviate the polycystic ovary syndrome with improved insulin sensitivity through PI3K/Akt signaling pathway [J] . Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2020,第期

机译：刘伟二光药丸缓解多囊卵巢综合征，通过PI3K / AKT信号通路改善胰岛素敏感性
4. Identification of Key Metabolic Pathways in Polycystic Ovary Syndrome by Mass Spectrometry, NMR and Cavity Ring-Down Spectroscopy [C] . Michael R. Shortreed, Fariba Assadi Porter, Leah D. Whigham, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：通过质谱，NMR和腔闭射光谱法鉴定多囊卵巢综合征的关键代谢途径
5. Validation of the obese Ossabaw miniature pig as a model of the obese polycystic ovary syndrome phenotype with concomitant metabolic syndrome: Exploration of polycystic ovary syndrome pathophysiology using in vivo and in vitro models [D] . Newell-Fugate, Anne Elizabeth 2012

机译：肥胖的Ossabaw小型猪作为肥胖多囊卵巢综合征表型伴有代谢综合征的模型的验证：利用体内和体外模型探索多囊卵巢综合征的病理生理学
6. Plumbagin inhibits proliferation and promotes apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inactivating PI3K/Akt/mTOR pathway [O] . Zhaowei Cai, Shaojuan He, Tao Li, 2020

机译：通过灭活PI3K / AKT / MTOR途径抑制肠果抑制多囊卵巢综合征中卵巢粒细胞的增殖和促进卵巢颗粒细胞凋亡
7. Protective Effects of Berberine on Rat Model of Polycystic Ovary Syndrome Through the PI3K/AKT Pathway [O] . Jia Yu, Caifei Ding, Zhoujia Hua, 2020

机译：小檗碱对通过PI3K / AKT路径的多囊卵巢综合征大鼠模型的保护作用

Beneficial effects of Heqi san on rat model of polycystic ovary syndrome through the PI3K/AKT pathway

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