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Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone

机译:激光尾场加速器作为硬X射线源用于人体骨骼的3D医学成像

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摘要

A bright μm-sized source of hard synchrotron x-rays (critical energy Ecrit > 30 keV) based on the betatron oscillations of laser wakefield accelerated electrons has been developed. The potential of this source for medical imaging was demonstrated by performing micro-computed tomography of a human femoral trabecular bone sample, allowing full 3D reconstruction to a resolution below 50 μm. The use of a 1 cm long wakefield accelerator means that the length of the beamline (excluding the laser) is dominated by the x-ray imaging distances rather than the electron acceleration distances. The source possesses high peak brightness, which allows each image to be recorded with a single exposure and reduces the time required for a full tomographic scan. These properties make this an interesting laboratory source for many tomographic imaging applications.
机译:基于激光尾场加速电子的倍增子振荡,已经开发出了一个明亮的μm大小的硬同步加速器X射线源(临界能量Ecrit> 30 keV)。通过对人类股骨小梁骨样品进行微计算机断层扫描,可以进行完整的3D重建,使其分辨率低于50μm,从而证明了这种医学成像源的潜力。使用1 cm长的尾场加速器意味着光束线(不包括激光器)的长度由X射线成像距离而不是电子加速距离决定。该光源具有很高的峰值亮度,可以一次曝光记录每张图像,并减少了完整的断层扫描所需的时间。这些特性使它成为许多层析成像应用程序的有趣实验室资源。

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