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Multi-component quantitative magnetic resonance imaging by phasor representation

机译:相量表示法的多分量定量磁共振成像

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摘要

Quantitative magnetic resonance imaging (qMRI) is a versatile, non-destructive and non-invasive tool in life, material, and medical sciences. When multiple components contribute to the signal in a single pixel, however, it is difficult to quantify their individual contributions and characteristic parameters. Here we introduce the concept of phasor representation to qMRI to disentangle the signals from multiple components in imaging data. Plotting the phasors allowed for decomposition, unmixing, segmentation and quantification of our in vivo data from a plant stem, a human and mouse brain and a human prostate. In human brain images, we could identify 3 main T 2 components and 3 apparent diffusion coefficients; in human prostate 5 main contributing spectral shapes were distinguished. The presented phasor analysis is model-free, fast and accurate. Moreover, we also show that it works for undersampled data.
机译:定量磁共振成像(qMRI)是生命,材料和医学领域中的一种多功能,无损且无创的工具。但是,当多个分量对单个像素中的信号有贡献时,很难量化它们各自的贡献和特征参数。在这里,我们将相量表示的概念引入qMRI,以消除来自成像数据中多个分量的信号。绘制相量可以分解,分解,分割和定量来自植物茎,人脑和小鼠脑以及人前列腺的体内数据。在人脑图像中,我们可以识别出3个主要的T 2成分和3个表观扩散系数。在人类前列腺中,有5种主要的光谱形状被区分出来。提出的相量分析是无模型的,快速而准确的。此外,我们还表明它适用于欠采样数据。

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