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A Novel Metamaterial-Inspired RF-coil for Preclinical Dual-Nuclei MRI

机译:临床前双核MRI的新型超材料启发的RF线圈

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摘要

In this paper, we propose, design and test a new dual-nuclei RF-coil inspired by wire metamaterial structures. The coil operates as a result of resonant excitation of hybridized eigenmodes in multimode flat periodic structures comprising several coupled thin metal strips. It was shown that the field distribution of the coil (i.e. penetration depth) can be controlled independently at two different Larmor frequencies by selecting a proper eigenmode in each of two mutually orthogonal periodic structures. The proposed coil requires no lumped capacitors to be tuned and matched. In order to demonstrate the performance of the new design, an experimental preclinical coil for 19F/1H imaging of small animals at 7.05T was engineered and tested on a homogeneous liquid phantom and in-vivo. The results demonstrate that the coil was both well tuned and matched at two Larmor frequencies and allowed image acquisition at both nuclei. In an in-vivo experiment, it was shown that without retuning the setup it was subsequently possible to obtain anatomical 1H images of a mouse under anesthesia with 19F images of a tiny tube filled with a fluorine-containing liquid and attached to the body of the mouse.
机译:在本文中,我们提出,设计和测试了受金属超材料结构启发的新型双核RF线圈。线圈是在包含多个耦合的薄金属条的多模平面周期结构中,对混合本征模式进行共振激励而工作的。已经表明,通过在两个相互正交的周期结构的每一个中选择适当的本征模,可以在两个不同的拉莫尔频率上独立地控制线圈的场分布(即,穿透深度)。提出的线圈不需要集总电容器进行调谐和匹配。为了证明新设计的性能,设计了一个实验性临床前线圈,用于在7.05T下对小动物进行 19 F / 1 H成像,并在均匀液体上进行了测试幻影和体内。结果表明,线圈在两个拉莫尔频率下均得到了很好的调谐和匹配,并允许在两个核上采集图像。在体内实验中,结果表明,无需重新调整设置,随后就有可能在麻醉下用鼠标的 19 F图像获取小鼠的解剖学 1 H图像。装满含氟液体并连接到老鼠身体的细管。

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