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Major reduction in asthma morbidity and continued reduction in asthma mortality in New Zealand: what lessons have been learned?

机译:新西兰的哮喘发病率大大降低哮喘死亡率持续降低:已经学到了什么?

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摘要

Increasing financial barriers to primary health care against a background of social and economic decline are likely to have contributed to asthma morbidity and mortality in New Zealand. Although there would not have been a sufficient increase in asthma prevalence to have accounted for the threefold increase in mortality rates, whether or not there was an increase in asthma severity in the late 1970s remains open to debate. Misuse or poor use of newly available and potent bronchodilator medications by those with the most severe asthma may simply have contributed to further delays in obtaining appropriate care and therefore to an increase in frequency of severe attacks in the community. Despite substantial increases in the use of bronchodilator therapy in New Zealand, there was no immediate improvement in indices of either asthma morbidity or mortality. The initial reduction in mortality rates in the 1980s happened at a time when first admissions for asthma were still increasing and seems to be best explained by an improvement in utilisation of hospital services (which were free until 1992) rather than a reduction in asthma severity. However, the recent reductions in all measures of asthma morbidity and further reduction in asthma mortality since 1989 does now suggest a reduction in asthma severity and would be best explained by the substantial increase in medium and high dose inhaled corticosteroid use, and to the endorsement of the current management strategies for asthma which are being promoted internationally and which were given considerable publicity in New Zealand in 1989 and 1990. Whilst sales of inhaled beta agonists were higher in 1991 than 1989, this may not reflect their pattern of use by individual patients since the need for an increase in inhaled beta agonist treatment has been accepted as indicating a lack of control and the need for either starting or increasing the dose of inhaled steroid treatment.
机译:在社会和经济下滑的背景下,增加对初级卫生保健的财政壁垒可能导致了新西兰的哮喘发病率和死亡率。尽管哮喘患病率没有足够的增加来说明死亡率增加了三倍,但在1970年代后期哮喘严重程度是否增加尚有争议。哮喘最严重的人滥用或滥用新的有效支气管扩张药可能只是进一步延迟了获得适当护理的时间,因此增加了社区严重发作的频率。尽管在新西兰使用支气管扩张药的方法大量增加,但哮喘发病率或死亡率指标并没有立即改善。死亡率的最初降低发生在1980年代,当时哮喘的首次住院人数仍在增加,这似乎最好的解释是医院服务利用率的提高(直到1992年才免费),而不是哮喘严重程度的降低。但是,自1989年以来,最近所有哮喘发病率指标的降低以及哮喘死亡率的进一步降低,现在确实表明哮喘的严重程度有所降低,这可以用中,高剂量吸入糖皮质激素的大量增加以及当前的哮喘管理策略正在国际上推广,并于1989年和1990年在新西兰得到了广泛宣传。虽然1991年吸入式β受体激动剂的销售量高于1989年,但这可能不能反映个体患者使用它们的模式,因为接受增加的β受体激动剂治疗的需要已被接受,因为这表明缺乏控制,并且需要开始或增加吸入类固醇治疗的剂量。

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