Structural Differences within Negative and Depressive Syndrome Dimensions in Schizophrenia Organic Brain Disease and Major Depression: A Confirmatory Factor Analysis of the Positive and Negative Syndrome Scale

摘要

ObjectiveThe emerging dimensional approach to classification and treatment of psychiatric disorders calls for better understanding of diagnosis-related variations in psychiatric syndromes and for proper validation of psychometric scales used for the evaluation of those syndromes. This study tested the hypothesis that negative and depressive syndromes as measured by the Positive and Negative Syndrome Scale (PANSS) are consistent across different diagnoses.