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Innate Immune Response and Outcome of Clostridium difficile Infection Are Dependent on Fecal Bacterial Composition in the Aged Host

机译：难辨梭状芽孢杆菌感染的先天免疫应答和结果取决于老年宿主的粪便细菌组成。

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Background Clostridium difficile infection (CDI) is a serious threat for an aging population. Using an aged mouse model, we evaluated the effect of age and the roles of innate immunity and intestinal microbiota.

机译：背景艰难梭菌感染（CDI）对于人口老龄化是一个严重的威胁。使用老年小鼠模型，我们评估了年龄的影响以及先天免疫和肠道菌群的作用。

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期刊名称 The Journal of Infectious Diseases
作者
Jae Hyun Shin; Yingnan Gao; John H Moore II; David T Bolick; Glynis L Kolling; Martin Wu; Cirle A Warren;
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作者单位

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年(卷),期 -1(217),2
年度 -1
页码 188–197
总页数 10
原文格式 PDF
正文语种
中图分类免疫学;微生物学;病毒传染病;
关键词
aging Clostridium difficile infection host response innate immunity microbiome;

机译：衰老;艰难梭菌感染;宿主反应;先天免疫;微生物组;

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专利

1. Innate Immune Response and Outcome of Clostridium difficile Infection Are Dependent on Fecal Bacterial Composition in the Aged Host [J] . Jae HyunShin, YingnanGao, John HMoore, The Journal of Infectious Diseases . 2018,第2期

机译：梭菌性艰难梭菌感染的先天免疫应答和结果依赖于老年宿主中的粪便细菌组合物
2. The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection [J] . SunX., HirotaS.A. Molecular Immunology . 2015,第2期

机译：宿主和病原体因素及先天免疫应答在艰难梭菌感染发病机理中的作用
3. The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection [J] . SunX., HirotaS.A. Molecular Immunology . 2014,第2期

机译：宿主和病原体因子的作用以及在梭菌差异感染发病机制中的先天免疫反应
4. Clostridium difficile Infection: the interplays of pathogen, commensal microbiota and host immune response [C] . Xinhua Chen 4th international symposium on dairy cow nutrition and milk quality proceedings . 2015

机译：艰难梭菌感染：病原体，共生菌群和宿主免疫反应的相互作用
5. Innate Immune Recognition of Conserved Structural Features of Bacterial Flagellin Shapes Host Antibody Responses. [D] . Lopez-Yglesias, Americo H. 2014

机译：细菌鞭毛形状的保守结构特征的固有免疫识别宿主抗体反应。
6. The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection [O] . Xingmin Sun, Simon A. Hirota -1

机译：宿主和病原体因素及先天免疫应答在艰难梭菌感染发病机理中的作用
7. 1014 - Microbiota Composition, Metabolic Profiles and Inflammatory Host Response after Fecal Microbiota Transplantation (FMT) for Recurrent Clostridium Difficile Infection. Does Proteobacteria Abundance Predict the Response to FMT? [O] . Serena Schippa, Giovanni Bruno, Clelia Cicerone, 2018

机译：1014 - 粪便微生物群移植（FMT）后微生物的组成，代谢谱和炎症宿主反应用于复发性梭菌感染。植物对丰度是否预测对FMT的反应？

Innate Immune Response and Outcome of Clostridium difficile Infection Are Dependent on Fecal Bacterial Composition in the Aged Host

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