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Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening

机译：在英国卵巢癌筛查合作试验中使用串行生物标志物测量的风险算法与单阈值规则相比筛查癌症的数量翻了一番

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PurposeCancer screening strategies have commonly adopted single-biomarker thresholds to identify abnormality. We investigated the impact of serial biomarker change interpreted through a risk algorithm on cancer detection rates.

机译：目的癌症筛查策略通常采用单一生物标志物阈值来识别异常。我们调查了通过风险算法解释的系列生物标志物变化对癌症检出率的影响。

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期刊名称 Journal of Clinical Oncology
作者
Usha Menon; Andy Ryan; Jatinderpal Kalsi; Aleksandra Gentry-Maharaj; Anne Dawnay; Mariam Habib; Sophia Apostolidou; Naveena Singh; Elizabeth Benjamin; Matthew Burnell; Susan Davies; Aarti Sharma; Richard Gunu; Keith Godfrey; Alberto Lopes; David Oram; Jonathan Herod; Karin Williamson; Mourad W. Seif; Howard Jenkins; Tim Mould; Robert Woolas; John B. Murdoch; Stephen Dobbs; Nazar N. Amso; Simon Leeson; Derek Cruickshank; Ian Scott; Lesley Fallowfield; Martin Widschwendter; Karina Reynolds; Alistair McGuire; Stuart Campbell; Mahesh Parmar; Steven J. Skates; Ian Jacobs;
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年(卷),期 -1(33),18
年度 -1
页码 2062–2071
总页数 14
原文格式 PDF
正文语种
中图分类肿瘤学;
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1. Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening [J] . Menon Usha, Ryan Andy, Kalsi Jatinderpal, Journal of Clinical Oncology . 2015,第18期

机译：在英国卵巢癌筛查合作试验中，使用串行生物标记物测量的风险算法与单阈值规则相比，筛查癌症的数量翻了一番
2. Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening [J] . Menon Usha, Ryan Andy, Kalsi Jatinderpal, Journal of Clinical Oncology . 2015,第18期

机译：使用串行生物标志物测量的风险算法将屏幕检测的癌症的数量加倍，与英国合作试验的卵巢癌筛查的单阈值规则相比
3. Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) [J] . Paul M Trembling, Sophia Apostolidou, Aleksandra Gentry-Maharaj, BMC Public Health . 2017,第1期

机译：体重指数，酒精及其相互作用导致绝经后妇女罹患慢性肝病的风险：英国卵巢癌筛查合作试验（UKCTOCS）中的一项前瞻性嵌套队列研究
4. Looking for Better Combination of Biomarker Selection and Classification Algorithm for Early Screening of Ovarian Cancer [C] . Yu-Seop Kim, Jong-Dae Kim, Min-Ki Jang, FTRA international scientific conference on multimedia and ubiquitous engineering;Workshop on advanced technologies and aplications for cloud computing and sensor networks;FTRA international workshop on pervasive services, systems and intelligence . 2013

机译：寻找更好地结合生物标志物选择和分类算法的卵巢癌早期筛查
5. Melanoma Risk Factors within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial [D] . Hyde, Mark A. 2017

机译：前列腺癌，肺癌，大肠癌和卵巢癌筛查试验中的黑色素瘤危险因素
6. Risk of chronic liver disease in post-menopausal women due to body mass index alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) [O] . Paul M Trembling, Sophia Apostolidou, Aleksandra Gentry-Maharaj, 2017

机译：体重指数酒精及其相互作用导致绝经后妇女罹患慢性肝病的风险：英国卵巢癌筛查合作试验（UKCTOCS）中的一项前瞻性嵌套队列研究
7. Risk algorithm using serial biomarker measurements doubles the number of screen-detected cancers compared with a single-threshold rule in the United Kingdom collaborative trial of ovarian cancer screening [O] . Menon Usha, Ryan Andy, Kalsi Jatinderpal, 2015

机译：与英国卵巢癌筛查合作试验的单阈值规则相比，使用串行生物标记物测量的风险算法使筛查检测到的癌症数量翻了一番

Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening

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