Genome Wide Association (GWA) Predictors Of Anti-TNFα Therapeutic Responsiveness In Pediatric Inflammatory Bowel Disease (IBD)

摘要

BackgroundInter-individual variation in response to anti-TNFα therapy may be explained by genetic variability in disease pathogenesis or mechanism of action. Recent genome wide association studies (GWAS) in IBD have increased our understanding of the genetic susceptibility to IBD.