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Incidence of Retinopathy of Prematurity in Extremely Premature Infants

机译:极早产儿早产儿视网膜病变的发生率

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摘要

Purpose. To investigate the incidence and the severity of retinopathy of prematurity (ROP) in extremely preterm infants born before 28 weeks of gestation in southeastern Turkey. Methods. A retrospective chart review was performed for infants born before 28 weeks of gestation. The following data were reviewed: gender, gestational age (GA), birth weight (BW), zone and stage of ROP, presence of plus disease, and treatment for ROP if needed. Infants were divided into 2 groups according to GA as follows: group 1 included infants of GAs 25 weeks and under; group 2 included infants of GAs less than 28 weeks and over 25 weeks. Results. The incidence of any ROP in the whole cohort, in group 1, and in group 2, was 66.0%, 95.5%, and 58.6%, respectively. Incidence of any ROP was significantly associated with BW and GA (P = 0.014 and P = 0.002, resp.). The overall incidence of type 1 ROP was 35.8% (59.1% in group 1 and 29.9% in group 2). Development of type 1 ROP was independently associated with GA. Conclusion. Any ROP was significantly associated with BW and GA. Extremely premature infants with lower GA were found to be more likely to develop type 1 ROP. BW cannot predict the development of type 1 ROP.
机译:目的。调查在土耳其东南部妊娠28周之前出生的极早产儿早产儿视网膜病变(ROP)的发生率和严重程度。方法。对妊娠28周之前出生的婴儿进行回顾性图表审查。审查了以下数据:性别,胎龄(GA),出生体重(BW),ROP的区域和阶段,是否存在疾病以及是否需要进行ROP治疗。根据GA将婴儿分为2组:第1组包括25周及以下的GA。第2组包括GAs小于28周和25周以上的婴儿。结果。在第1组和第2组中,整个队列中任何ROP的发生率分别为66.0%,95.5%和58.6%。任何ROP的发生都与体重和GA显着相关(分别为P = 0.014和P = 0.002)。 1型ROP的总发生率为35.8%(第1组为59.1%,第2组为29.9%)。 1型ROP的发生与GA独立相关。结论。任何ROP与BW和GA均显着相关。发现GA极低的极早产婴儿更容易发生1型ROP。 BW无法预测1型ROP的发展。

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