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Glutamate microinjection into the hypothalamic paraventricular nucleus attenuates ulcerative colitis in rats

机译：向下丘脑室旁核注射谷氨酸盐可减轻大鼠溃疡性结肠炎

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摘要

Aim:To investigate the effects of glutamate microinjection into hypothalamic paraventricular nucleus (PVN) on ulcerative colitis (UC) in rats and to explore the relevant mechanisms.

机译：目的：探讨向下丘脑室旁核（PVN）内注射谷氨酸对大鼠溃疡性结肠炎（UC）的影响，并探讨其相关机制。

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期刊名称 Acta Pharmacologica Sinica
作者
Ting-ting Li; Jian-fu Zhang; Su-juan Fei; Sheng-ping Zhu; Jin-zhou Zhu; Xiao Qiao; Zhang-bo Liu;
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作者单位

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年(卷),期 2014(35),2
年度 2014
页码 185–194
总页数 10
原文格式 PDF
正文语种
中图分类药学;
关键词
ulcerative colitis 246-trinitrobenzenesulfonic acid glutamate kainic acid arginine vasopressin hypothalamus paraventricular nucleus nucleus tractus solitarius vagus;

机译：溃疡性结肠炎;246-三硝基苯磺酸;谷氨酸;海藻酸;精氨酸升压素;下丘脑;脑室旁核;孤束核;迷走神经;

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专利

1. Glutamate microinjection into the hypothalamic paraventricular nucleus attenuates ulcerative colitis in rats [J] . Ting-ting LI, Jian-fu ZHANG, Su-juan FEI, 中国药理学报：英文版 . 2014,第002期

机译：谷氨酸微量注入下丘脑室旁核可减轻大鼠溃疡性结肠炎
2. Involvement of non-NMDA glutamate receptors of the hypothalamic paraventricular nucleus in the cardiovascular response to the microinjection of noradrenaline into the dorsal periaqueductal gray area of rats [J] . Pelosi Gislaine Garcia, Busnardo Cristiane, Tavares Rodrigo Fiacadori, Brain research . 2015,第Null期

机译：下丘脑室旁核非NMDA谷氨酸受体参与对去甲肾上腺素微量注入大鼠背周导水管灰色区的心血管反应
3. Role of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the cardiovascular effects of L-glutamate microinjection into the hypothalamic paraventricular nucleus of unanesthetized rats. [J] . Busnardo C, Tavares RF, Correa FM Journal of Neuroscience Research . 2009,第9期

机译：N-甲基-D-天冬氨酸和非N-甲基-D-天冬氨酸受体在未麻醉大鼠下丘脑室旁核微注射L-谷氨酸的心血管作用中的作用。
4. Distal colitis as a special pattern of ulcerative colitis [C] . I. L. KHALIF, N. S. MALAKHOV Falk Symposium . 2007

机译：远端结肠炎作为溃疡性结肠炎的特殊模式
5. Electrophysiological effects of angiotensin II on hypothalamic paraventricular nucleus neurons of the rat [D] . Latchford, Kevin Jason 2008

机译：血管紧张素II对大鼠下丘脑腺腺内核神经元的电生理学作用
6. Hypothalamic paraventricular nucleus stimulation reduces intestinal injury in rats with ulcerative colitis [O] . Quan-Jun Deng, Ding-Jing Deng, Jin Che, 2016

机译：下丘脑脑室旁核刺激减轻溃疡性结肠炎大鼠的肠损伤
7. Exercise training attenuates renovascular hypertension partly via RAS- ROS- glutamate pathway in the hypothalamic paraventricular nucleus [O] . Yan Zhang, Xiao-Jing Yu, Wen-Sheng Chen, 2016

机译：运动训练部分通过下丘脑腺腺核心核（Ras-谷氨酸途径）部分通过Ras-谷氨酸途径衰减肾血管性高血压
8. Immunohistochemical Differentiation of Electrophysiologically Defined NeuronalPopulations in the Region of the Rat Hypothalamic Paraventricular Nucleus [R] . Hoffman, N. W., Tasker, J. G., Dudek, F. E. 1991

机译：大鼠下丘脑室旁核区电生理定义神经元的免疫组化分化

Glutamate microinjection into the hypothalamic paraventricular nucleus attenuates ulcerative colitis in rats

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