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美国卫生研究院文献>AIDS Research and Therapy
>Standardized representation visualization and searchable repository of antiretroviral treatment-change episodes
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Standardized representation visualization and searchable repository of antiretroviral treatment-change episodes
BackgroundTo identify the determinants of successful antiretroviral (ARV) therapy, researchers study the virological responses to treatment-change episodes (TCEs) accompanied by baseline plasma HIV-1 RNA levels, CD4+ T lymphocyte counts, and genotypic resistance data. Such studies, however, often differ in their inclusion and virological response criteria making direct comparisons of study results problematic. Moreover, the absence of a standard method for representing the data comprising a TCE makes it difficult to apply uniform criteria in the analysis of published studies of TCEs.
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