首页> 美国卫生研究院文献>Acta Orthopaedica >Cementing does not increase the immediate postoperative risk of death after total hip arthroplasty or hemiarthroplasty: a hospital-based study of 10677 patients
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Cementing does not increase the immediate postoperative risk of death after total hip arthroplasty or hemiarthroplasty: a hospital-based study of 10677 patients

机译:固结不会增加全髋关节置换或半髋置换术后死亡的立即术后风险:一项基于医院的研究涉及10677名患者

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摘要

Background and purpose — It has been suggested that cemented arthroplasty is associated with increased peri- and postoperative mortality due to bone cement implanting syndrome, especially in fracture surgery. We investigated such an association in elective total hip arthroplasty (THA) patients and hemiarthroplasty (HA) patients treated for femoral neck fracture.Patients and methods — All 10,677 patients receiving elective THA or HA for fracture in our hospital between 2004 and 2015 were identified. Mortality rates for cemented and uncemented THA and HA were compared at different times postoperatively using logistic regression analysis. Analysis was adjusted for age, sex, ASA class, and year of surgery.Results — Adjusted 10- and 30-day mortality after cemented THA was comparable to that of the uncemented THA (OR 1.7; 95% CI 0.3–8.7 and OR 1.6; CI 0.7–3.6, respectively). There was no statistically significant difference in the adjusted 2-day mortality in the cemented HA group when compared with the uncemented group. However, in a subgroup analyses of ASA-class IV HA patients there was a difference, statistically not significant, during the first 2 days postoperatively in the cemented HA group compared with the uncemented HA group (OR 2.1; CI 0.9–4.7).Interpretation — Cementing may still be a safe option in both elective and hip fracture arthroplasty. Excess mortality of cemented THA and HA in the longer term is comorbidity related, not due to bone cement implantation syndrome. However, in the most fragile HA patient group caution is needed at the moment of cementing.
机译:背景与目的—有人认为,由于骨水泥植入综合征,尤其是在骨折手术中,骨水泥置换术与围手术期和术后死亡率增加有关。我们调查了选择性全髋关节置换(THA)和半髋置换(HA)股骨颈骨折接受治疗的患者之间的这种关联。患者和方法—确定了2004年至2015年间在我院接受选择性THA或HA骨折的所有10,677例患者。使用逻辑回归分析比较术后不同时间骨水泥和未骨水泥THA和HA的死亡率。分析结果针对年龄,性别,ASA类别和手术年份进行了调整。结果-合并THA后的10天和30天调整后死亡率与未合并THA相当(OR 1.7; 95%CI 0.3-8.7和OR 1.6 ; CI分别为0.7-3.6)。与未骨水泥治疗组相比,骨水泥治疗HA组经调整的2天死亡率无统计学差异。但是,在对ASA IV级HA患者进行的亚组分析中,与非骨水泥HA组相比,骨水泥HA组术后头2天与非骨水泥HA组有统计学差异(OR 2.1; CI 0.9-4.7)。 —在择期和髋部骨折置换术中,固井可能仍然是安全的选择。长期而言,胶结的THA和HA的超额死亡率与合并症相关,而不是由于骨水泥植入综合征。但是,在最脆弱的HA患者组中,在固定时需要注意。

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