首页> 美国卫生研究院文献>Acta Orthopaedica >Inadequate evaluation and management of suspected ­infections after TKA surgery in Lithuania: a retrospective study of 2769 patients with 2-year follow-up
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Inadequate evaluation and management of suspected ­infections after TKA surgery in Lithuania: a retrospective study of 2769 patients with 2-year follow-up

机译:立陶宛TKA手术后可疑感染的评估和处理不充分:对2769例患者进行了为期2年的随访研究

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摘要

Background and purpose — The evidence-based algorithms for treatment of periprosthetic joint infection (PJI) recommend surgical intervention in combination with the use of systemic antibiotics. However, still it is not unusual to treat total knee arthroplasty (TKA) patients with suspected infection using only antibiotics. We investigated treatment pathways for TKA patients with suspected infection in Lithuania.Patients and methods — Of the 4,069 TKA patients (4,269 knees) registered in the Lithuanian Arthroplasty Register (2013–2015) 2,769 patients (2,825 knees) were interviewed 2 years after the surgery. The patients were asked if they had been subject to antibiotic treatment after the TKA surgery and/or if any additional surgical interventions on the operated knee had been performed. The number of patients treated with antibiotics due to problems in the operated knee was identified and cumulative revision rates (CRR) were calculated.Results — 180 (7%) patients of the total 2,769 reported that they had been prescribed antibiotics after the primary TKA; 132 of these patients (70%) said they had received antibiotics due to problems with the operated knee. The 2-year CRR after TKA in patients not treated with antibiotics was 0.7% (95% CI 0.4–1), as compared with 24% (95% CI 17–32) in those who had used antibiotics due to the problems in the operated knee for more than 1 week.Interpretation — In Lithuania there seems to be a lack of adherence to evidence-based treatment guidelines when infection is suspected after primary TKA.
机译:背景与目的—用于治疗假体周围关节感染(PJI)的基于证据的算法建议将手术干预与全身性抗生素结合使用。但是,仅使用抗生素治疗怀疑感染的全膝关节置换术(TKA)患者仍然并不罕见。我们调查了立陶宛疑似感染的TKA患者的治疗途径。患者和方法—手术2年后,对立陶宛人工关节置换术登记册(2013-2015)登记的4,069例TKA患者(4,269膝)进行了访谈,共2,769例患者(2,825膝)。 。询问患者在TKA手术后是否接受过抗生素治疗和/或是否对手术膝盖进行了其他外科手术。确定了因手术膝盖问题而接受抗生素治疗的患者人数,并计算了累积翻修率(CRR)。结果—在2,769例患者中,有180例(7%)报告说他们在初次TKA后被开了抗生素。这些患者中有132名(70%)表示由于膝盖手术问题而接受了抗生素治疗。未经抗生素治疗的患者在TKA后的2年CRR为0.7%(95%CI 0.4-1),而由于抗生素治疗中的问题而使用抗生素的患者则为24%(95%CI 17–32)。手术超过1周。解释—在立陶宛,当怀疑是原发性TKA后感染时,似乎缺乏循证治疗指南。

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