The USC*PACK PC programs for population pharmacokinetic modeling modeling of large kinetic/dynamic systems and adaptive control of drug dosage regimens.

摘要

Programs for PC's and compatibles provide nonparametric (NPEM) population pharmacokinetic modeling, BOXES for compartments and arrows for pathways, to make large kinetic and dynamic models, and clinical software for Bayesian adaptive control of drug dosage regimens, with D-optimal sampling strategies and explicit determination of assay error patterns.