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Extracting and standardizing medication information in clinical text – the MedEx-UIMA system

机译:在临床文本中提取和标准化药物信息– MedEx-UIMA系统

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摘要

Extraction of medication information embedded in clinical text is important for research using electronic health records (EHRs). However, most of current medication information extraction systems identify drug and signature entities without mapping them to standard representation. In this study, we introduced the open source Java implementation of MedEx, an existing high-performance medication information extraction system, based on the Unstructured Information Management Architecture (UIMA) framework. In addition, we developed new encoding modules in the MedEx-UIMA system, which mapped an extracted drug name/dose/form to both generalized and specific RxNorm concepts and translated drug frequency information to ISO standard. We processed 826 documents by both systems and verified that MedEx-UIMA and MedEx (the Python version) performed similarly by comparing both results. Using two manually annotated test sets that contained 300 drug entries from medication list and 300 drug entries from narrative reports, the MedEx-UIMA system achieved F-measures of 98.5% and 97.5% respectively for encoding drug names to corresponding RxNorm generic drug ingredients, and F-measures of 85.4% and 88.1% respectively for mapping drug names/dose/form to the most specific RxNorm concepts. It also achieved an F-measure of 90.4% for normalizing frequency information to ISO standard. The open source MedEx-UIMA system is freely available online at .
机译:提取嵌入临床文本中的药物信息对于使用电子健康记录(EHR)的研究非常重要。然而,当前大多数的药物信息提取系统都在不将药物和签名实体映射到标准表示的情况下对其进行识别。在这项研究中,我们介绍了基于非结构化信息管理架构(UIMA)框架的MedEx的开源Java实现,MedEx是一个现有的高性能药物信息提取系统。此外,我们在MedEx-UIMA系统中开发了新的编码模块,该模块将提取的药物名称/剂量/形式映射到通用和特定的RxNorm概念,并将药物频率信息转换为ISO标准。我们通过两个系统处理了826个文档,并通过比较两个结果验证了MedEx-UIMA和MedEx(Python版本)的相似性能。通过使用两个手动注释的测试集,其中包含药物清单中的300个药物条目和叙述报告中的300个药物条目,MedEx-UIMA系统分别实现了98.5%和97.5%的F度量,以便将药物名称编码为相应的RxNorm通用药物成分,并且将药物名称/剂量/形式映射到最具体的RxNorm概念的F值分别为85.4%和88.1%。它还实现了90.4%的F量度,以将频率信息标准化为ISO标准。开源MedEx-UIMA系统可在上免费在线获取。

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