EFFECTS OF COMBINED EXTRACTS OF DOLICHOS BIFLORUS SEEDS AND AMARANTHUS SPINOSUS ROOTS ON THE ACCESSORY SEX ORGANS OF MALE RATS

摘要

Biological effects of extracts of Dolichos biflorus seeds and Amaranthus spinosus roots administered at two different doses (25 mg of D.biflorus seeds and 25 mg of A.spinosus roots; 50mg of D.biflorus seedsand 50 mg of A.spinosus roots) for 10 consecutive days were studied in the accessory sex organs of adult male rats. The observed adverse effect on organs weight, protein content and concentration as well as the enzymatic activities in the vas defers, seminal vesicle and ventral prostate indicates the probable antiandrogenic action of the drug in the male rats.