The Road to Hell Is Paved with Good Intentions: Why Harm–Benefit Analysis and Its Emphasis on Practical Benefit Jeopardizes the Credibility of Research

摘要

Simple SummaryThe European legislation on project evaluation of animal research has recently changed. Every procedure on live non-human vertebrates and cephalopods has to be approved in a project evaluation (harm–benefit analysis (HBA)) that weighs the inflicted harms on animals against potential prospective benefits. Recent publications on the HBA prioritise “societal benefits” that have a foreseeable, positive impact on humans, animals, or the environment over gaining knowledge (e.g., basic research). However, we argue that whether potential prospective societal benefits are realized is (a) impossible to predict and (b) exceeds the scope and responsibility of researchers. Furthermore, the emphasis on practical benefits has the drawback of driving researchers into speculation on the practical benefit of their research and, therefore, into promising too much. Repeated failure to deliver proclaimed practical benefits will lead to a loss of trust and credibility in research. The concepts of benefit and benefit assessment in the HBA, as well as the HBA itself, require re-evaluation in a spirit that embraces the value of knowledge in our society. Research projects should be measured by the quality of the research they perform and by the contributions they make to a specific field of research or research program. Only then can promises regarding benefits (in terms of knowledge) be kept and continued public trust ensured. Time and again, scientific knowledge has been utilized to great benefit for humans, animals, and the environment. The HBA, as it currently stands, tends to turn this idea upside down and implies that research is of value only if the resulting findings bring about direct practical benefits, which science itself can neither provide nor guarantee. The road to hell is, as the saying goes, paved with good intentions.