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Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial

机译：低剂量率直肠内近距离放射治疗在局部晚期直肠癌治疗中新辅助化学放疗的疗效和安全性：II期临床试验

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PurposeDespite advances in rectal cancer treatment over the last decade, local control and risk of late side effects due to external beam radiation therapy (EBRT) remain as concerns. The present study aimed to investigate the efficacy and the safety of low-dose-rate endorectal brachytherapy (LDRBT) as a boost to neoadjuvant chemoradiation for use in treating locally advanced distal rectal adenocarcinomas.

机译：目的尽管在过去十年中直肠癌治疗取得了进步，但仍需要关注局部控制以及由于外部束放射疗法（EBRT）引起的后期副作用的风险。本研究旨在调查低剂量率直肠内近距离放射治疗（LDRBT）作为新辅助化学放疗的增强剂的疗效和安全性，该新辅助化学放疗用于治疗局部晚期直肠远端腺癌。

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期刊名称 Annals of Coloproctology
作者
Shapour Omidvari; Shadi Zohourinia; Mansour Ansari; Leila Ghahramani; Mohammad Zare-Bandamiri; Ahmad Mosalaei; Niloofar Ahmadloo; Saeedeh Pourahmad; Hamid Nasrolahi; Sayed Hasan Hamedi; Mohammad Mohammadianpanah;
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年(卷),期 2015(31),4
年度 2015
页码 123–130
总页数 8
原文格式 PDF
正文语种
中图分类外科学;
关键词
Rectal neoplasms Adenocarcinoma Brachytherapy Neoadjuvant treatment Surgery;

机译：直肠肿瘤;腺癌;近距离放射治疗;新辅助治疗;手术;

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专利

1. 奥沙利铂和卡培他滨联合贝伐单抗加放疗的新辅助方案治疗局部晚期直肠癌:单中心Ⅱ期研究结果 [J] . Xin Yu, De-sen Wan, Pei-rong Ding, 癌症（英文版） . 2018,第008期
2. Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial [J] . Omidvari Shapour, Zohourinia Shadi, Ansari Mansour, Annals of Coloproctology . 2015,第4期

机译：低剂量率直肠内近距离放射疗法作为新辅助化学放疗在局部晚期直肠癌治疗中的疗效和安全性：II期临床试验
3. Is Low-Dose-Rate Endorectal Brachytherapy a New Treatment Method for Locally Advanced Distal Rectal Cancer? [J] . Baik Seung Hyuk Annals of Coloproctology . 2015,第4期

机译：低剂量率直肠内近距离放射治疗是局部晚期直肠癌的一种新治疗方法吗？
4. Preoperative endorectal brachytherapy in the treatment of locally advanced rectal cancer: Rethinking neoadjuvant treatment [J] . Matthew C. Biagioli, Joseph M. Herman Seminars in colon and rectal surgery . 2014,第1期

机译：术前直肠内近距离放射疗法治疗局部晚期直肠癌：新辅助治疗的反思
5. Neoadjuvant treatment in rectal cancer: do we always need radiotherapy-or can we risk assess locally advanced rectal cancer better? [C] . Rob Glynne-Jones St. Gallen EORTC Gastrointestinal Cancer Conference . 2012

机译：Neoadjuvant在直肠癌中治疗：我们总是需要放射治疗 - 或者我们是否可以更好地评估当地先进的直肠癌？
6. Intenzivnej?e neoadjuvantno zdravljenje lokalno napredovalnega raka danke =Intensified neoadjuvant treatment of locally advanced rectal cancer [D] . Golo, Danijela. 2018

机译：强烈的Neoadjuvant治疗局部晚期癌症射线=加强Neoadjuvant治疗局部晚期直肠癌
7. Is Low-Dose-Rate Endorectal Brachytherapy a New Treatment Method for Locally Advanced Distal Rectal Cancer? [O] . Seung Hyuk Baik 2015

机译：低剂量率直肠内近距离放射治疗是局部晚期直肠癌的新治疗方法吗？
8. Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial [O] . Shapour Omidvari, Shadi Zohourinia, Mansour Ansari, 2015

机译：低剂量血液胸腔放射治疗的疗效和安全性作为局部晚期远端癌症治疗中的新辅助化学校长：II期临床试验

Efficacy and Safety of Low-Dose-Rate Endorectal Brachytherapy as a Boost to Neoadjuvant Chemoradiation in the Treatment of Locally Advanced Distal Rectal Cancer: A Phase-II Clinical Trial

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