首页> 美国卫生研究院文献>Antimicrobial Agents and Chemotherapy >Complex Class 1 Integrons with Diverse Variable Regions Including aac(6′)-Ib-cr and a Novel Allele qnrB10 Associated with ISCR1 in Clinical Enterobacterial Isolates from Argentina
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Complex Class 1 Integrons with Diverse Variable Regions Including aac(6′)-Ib-cr and a Novel Allele qnrB10 Associated with ISCR1 in Clinical Enterobacterial Isolates from Argentina

机译:来自阿根廷的临床肠杆菌分离物中具有多种可变区的复杂1类整合素包括aac(6-Ib-cr)和新型等位基因qnrB10与ISCR1相关联

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摘要

Transferable quinolone resistance has not previously been reported in Argentina. Here we describe three complex class 1 integrons harboring the novel allele qnrB10 in a unique region downstream of orf513, one of them also containing aac(6′)-Ib-cr within the variable region of integrons. The three arrays differed from blaCTX-M-2-bearing integrons, which are broadly distributed in Argentina.
机译:阿根廷尚未报道可转移的喹诺酮耐药性。在这里,我们描述了三个复杂的1类整合素,它们在orf513下游的一个独特区域中具有新颖的等位基因qnrB10,其中之一在整合素的可变区域内还包含aac(6')-Ib-cr。这三个阵列与blaCTX-M-2整合素不同,后者在阿根廷广泛分布。

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