首页> 美国卫生研究院文献>Antimicrobial Agents and Chemotherapy >Correlation between Ceftriaxone Resistance of Salmonella enterica Serovar Typhimurium and Expression of Outer Membrane Proteins OmpW and Ail/OmpX-Like Protein Which Are Regulated by BaeR of a Two-Component System
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Correlation between Ceftriaxone Resistance of Salmonella enterica Serovar Typhimurium and Expression of Outer Membrane Proteins OmpW and Ail/OmpX-Like Protein Which Are Regulated by BaeR of a Two-Component System

机译:肠沙门氏菌血清型鼠伤寒杆菌对头孢曲松的耐药性与外膜蛋白OmpW和Ail / OmpX-like蛋白表达的相关性该蛋白受两组分系统的BaeR调节

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摘要

Mutant 7F2 of Salmonella enterica serovar Typhimurium has a transposon inserted in the regulator gene baeR of a two-component system and showed a more-than-fourfold reduction in resistance to ceftriaxone. Complementation analysis suggested an association among the outer membrane proteins OmpW and STM3031, ceftriaxone resistance, and baeR.
机译:鼠伤寒沙门氏菌鼠伤寒沙门氏菌的突变体7F2在两组分系统的调节基因baeR中插入了一个转座子,对头孢曲松的耐药性降低了四倍以上。互补分析表明外膜蛋白OmpW和STM3031,头孢曲松抗性和baeR之间存在关联。

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