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Application of a Microcomputer-Based System to Control and Monitor Bacterial Growth

机译:基于微机的系统在细菌生长控制与监测中的应用

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摘要

A modular microcomputer-based system was developed to control and monitor various modes of bacterial growth. The control system was composed of an Apple II Plus microcomputer with 64-kilobyte random-access memory; a Cyborg ISAAC model 91A multichannel analog-to-digital and digital-to-analog converter; paired MRR-1 pH, pO2, and foam control units; and in-house-designed relay, servo control, and turbidimetry systems. To demonstrate the flexibility of the system, we grew bacteria under various computer-controlled and monitored modes of growth, including batch, turbidostat, and chemostat systems. The Apple-ISAAC system was programmed in Labsoft BASIC (extended Applesoft) with an average control program using ca. 6 to 8 kilobytes of memory and up to 30 kilobytes for datum arrays. This modular microcomputer-based control system was easily coupled to laboratory scale fermentors for a variety of fermentations.
机译:开发了基于模块化微型计算机的系统,以控制和监视细菌生长的各种模式。控制系统由一台Apple II Plus微型计算机和64 KB随机存取存储器组成。 Cyborg ISAAC 91A型多通道模数和数模转换器;配对的MRR-1 pH,pO2和泡沫控制单元;以及内部设计的继电器,伺服控制和比浊系统。为了证明系统的灵活性,我们在各种计算机控制和监控的生长模式下培养细菌,包括分批,turbidostat和chemostat系统。 Apple-ISAAC系统是在Labsoft BASIC(扩展为Applesoft)中编程的,平均控制程序使用ca。 6至8 KB的内存,基准数组最多30 KB。这种基于微型计算机的模块化控制系统可轻松连接到实验室规模的发酵罐,以进行各种发酵。

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