Engineering and microbiological tests indicated that a typical, commercial laminar airflow cabinet was not effective in providing either product protection or agent containment. The cabinet was modified and tested through a series of alternate configurations to establish a set of design criteria. A mock-up cabinet was developed from these design criteria. The mock-up unit was evaluated for efficiency in providing both product protection and agent containment. In these evaluations, challenge methods were developed to simulate normal, in-use laboratory operations. Controlled bacterial or viral aerosol challenges were used at higher than normal levels to provide stringent test conditions. Test results indicated that the mock-up unit was considerably better in preventing agent penetration (0.1 to 0.2 particles per 100 ft3 of air) than the commercial cabinet (5 to 6 particles per 100 ft3 of air) during product protection tests. Similarly, agent containment was considerably better in the new cabinet (particle escape of 2 to 3 per 100 ft3 of air at only one of the five test sites) than in the commercial cabinet (particle escape of 2 to 14 per 100 ft3 of air at three of the five test sites).
展开▼
机译：工程和微生物学测试表明，典型的商用层流气流柜无法有效地提供产品保护或隔离剂。通过一系列替代配置对机柜进行了修改和测试，以建立一套设计标准。根据这些设计标准开发了一个模拟柜。对样机单元进行了评估，以提供产品保护和灭火剂防护。在这些评估中，开发了挑战方法来模拟正常的，在使用中的实验室操作。控制细菌或病毒气雾剂的挑战浓度高于正常水平，以提供严格的测试条件。测试结果表明，该样机单元在防止试剂渗透方面（每100 ft 3 空气中有0.1到0.2个颗粒）比商用橱柜（每100 ft 中有5到6个颗粒）要好得多。 3 空气）在产品保护测试中。同样，在新的机柜中（每个五个测试点中只有一个测试点，每100 ft 3 空气中有2到3个微粒逸出）比在商用机柜中（2个微粒逸出2个）要好得多。五个测试站点中的三个站点中每100 ft 3 的空气中有14个）。
展开▼
