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Efficacy of vancomycin-releasing biodegradable poly(lactide-co-glycolide) antibiotics beads for treatment of experimental bone infection due to Staphylococcus aureus

机译：释放万古霉素的可生物降解的聚（丙交酯-共-乙交酯）抗生素微球治疗金黄色葡萄球菌引起的实验性骨感染的功效

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BackgroundClinical experience and animal studies have suggested that positron emission tomography (PET) using fluorine-18-labeled fluorodeoxyglucose (¹⁸F-FDG) may be promising for imaging of bone infections. In this study, we aimed to establish the accuracy of ¹⁸F-FDG PET scanning for monitoring the response to poly(lactide-co-glycolide) (PLGA) vancomycin beads for treatment of bone infection.

机译：背景技术临床经验和动物研究表明，使用氟18标记的氟脱氧葡萄糖（^{18 F-FDG）进行的正电子发射断层扫描（PET）可能有望用于骨感染的成像。在这项研究中，我们旨在确定^{18 F-FDG PET扫描的准确性，以监测对聚乳酸丙交酯（PLGA）万古霉素珠治疗骨感染的反应。}}

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期刊名称 Journal of Orthopaedic Surgery and Research
作者
Steve W. N. Ueng; Song-Shu Lin; I-Chun Wang; Chuen-Yung Yang; Ru-Chin Cheng; Shih-Jung Liu; Err-Cheng Chan; Cheng-Fen Lai; Li-Jen Yuan; Sheng-Chieh Chan;
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年(卷),期 2016(11),-1
年度 2016
页码 52
总页数 9
原文格式 PDF
正文语种
中图分类矫形学;
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1. Comparative Efficacies of Quinupristin-Dalfopristin, Linezolid, Vancomycin, and Ciprofloxacin in Treatment, Using the Antibiotic-Lock Technique, of Experimental Catheter-Related Infection Due to Staphylococcus aureus. [J] . Giacometti A, Cirioni O, Ghiselli R, Antimicrobial agents and chemotherapy. . 2005,第10期

机译：奎奴普林汀-达福普汀，利奈唑胺，万古霉素和环丙沙星在使用抗生素锁定技术治疗金黄色葡萄球菌引起的与导管相关的感染中的比较疗效。
2. Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study [J] . Felix Greimel, Christine Scheuerer, Andre Gessner, Drug Design, Development and Therapy . 2017,第5期

机译：莫西沙星，氟氯西林，利福平和联合疗法对抗生素治疗植入物相关的金黄色葡萄球菌感染的有效性：一项动物研究
3. Intracellular antimicrobial activity appearing as a relevant factor in antibiotic efficacy against an experimental foreign-body infection caused by Staphylococcus aureus [J] . O. Murillo1* M. E. Pachón1 G. Euba1 R. Verdaguer2 M. Carreras3 C. Cabellos1 J. Cabo4 F. Gudiol1 and J. Ariza1 Journal of Antimicrobial Chemotherapy . 2009,第5期

机译：细胞内抗菌活性是抗金黄色葡萄球菌引起的实验性异物感染的抗生素功效的相关因素
4. Efficacy of Antibiotic Treatment and Vaccination on Subclinical Mastitis Caused by Staphylococcus aureus [C] . Eduardo de S. C. Pinheiro, Felipe Z. Freitas, Marcos V. dos Santos Annual Meeting of the National Mastitis Council . 2015

机译：抗生素治疗和疫苗接种对由金黄色葡萄球菌引起的亚临床乳腺炎的疗效
5. A retrospective study to evaluate the efficacy of trimethoprim/sulfamethoxazole (TMP/SMX) compared to Daptomycin or Linezolid for the treatment of infections due to methicillin-resistant Staphylococcus aureus (MRSA). [D] . Poona Murari, Aparna Lakshmi. 2012

机译：回顾性研究评估甲氧苄氨嘧啶/磺胺甲恶唑（TMP / SMX）与达托霉素或利奈唑胺相比在治疗耐甲氧西林金黄色葡萄球菌（MRSA）感染中的疗效。
6. Antibiotic-loaded plaster of Paris implants coated with poly lactide-co-glycolide as a controlled release delivery system for the treatment of bone infections [O] . M.-A. Benoit, B. Mousset, C. Delloye, 1998

机译：填充有聚丙交酯-共-乙交酯涂层的巴黎植入物的抗菌药膏作为控释递送系统用于治疗骨感染
7. Efficacy of vancomycin-releasing biodegradable poly(lactide-co-glycolide) antibiotics beads for treatment of experimental bone infection due to Staphylococcus aureus [O] . Steve W. N. Ueng, Song-Shu Lin, I-Chun Wang, 2016

机译：释放万古霉素的可生物降解的聚（丙交酯-共-乙交酯）抗生素微珠治疗金黄色葡萄球菌引起的实验性骨感染的功效

Efficacy of vancomycin-releasing biodegradable poly(lactide-co-glycolide) antibiotics beads for treatment of experimental bone infection due to Staphylococcus aureus

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